Faculty of Medicine, Section of Physiological Acoustics and Communication, Eberhard Karls University Tübingen, Elfriede-Aulhorn-Strasse 5, 72076 Tübingen, Germany.
J Acoust Soc Am. 2011 Dec;130(6):3852-72. doi: 10.1121/1.3651822.
Coupling of somatic electromechanical force from the outer hair cells (OHCs) into the organ of Corti is investigated by measuring transverse vibration patterns of the organ of Cori and tectorial membrane (TM) in response to intracochlear electrical stimulation. Measurement places at the organ of Corti extend from the inner sulcus cells to Hensen's cells and at the lower (and upper) surface of the TM from the inner sulcus to the OHC region. These locations are in the neighborhood of where electromechanical force is coupled into (1) the mechanoelectrical transducers of the stereocilia and (2) fluids of the organ of Corti. Experiments are conducted in the first, second, and third cochlear turns of an in vitro preparation of the adult guinea pig cochlea. Vibration measurements are made at functionally relevant stimulus frequencies (0.48-68 kHz) and response amplitudes (<15 nm). The experiments provide phase relations between the different structures, which, dependent on frequency range and longitudinal cochlear position, include in-phase transverse motions of the TM, counterphasic transverse motions between the inner hair cell and OHCs, as well as traveling-wave motion of Hensen's cells in the radial direction. Mechanics of sound processing in the cochlea are discussed based on these phase relationships.
通过测量毛细胞（OHCs）的外毛细胞的体机电力耦合到耳蜗内的电刺激的情况下，科蒂器官和盖膜（TM）的横向振动模式来研究。在科蒂器官上的测量位置从内沟细胞延伸到Hensen 细胞，在 TM 的下（和上）表面从内沟延伸到 OHC 区域。这些位置在机电力耦合到（1）纤毛的机电换能器和（2）科蒂器官的流体的地方附近。实验在成年豚鼠耳蜗的体外制剂的第一，第二和第三耳蜗中进行。在功能相关的刺激频率（0.48-68 kHz）和响应幅度（<15nm）下进行振动测量。这些实验提供了不同结构之间的相位关系，这些相位关系取决于频率范围和纵向耳蜗位置，包括 TM 的同相横向运动、内毛细胞和 OHC 之间的反相横向运动，以及 Hensen 细胞的行波运动径向方向。基于这些相位关系，讨论了耳蜗中声音处理的力学。
