Department of Radiology, the First Affiliated Hospital of Guangzhou Medical College, Guangzhou, Guangdong, P.R. China.
Clin Imaging. 2012 Jan-Feb;36(1):8-13. doi: 10.1016/j.clinimag.2011.03.003.
This study aimed to analyze the computed tomographic (CT) various findings of mucoepidermoid carcinoma of the lung and to improve the diagnostic efficacy for such tumor.
Sixteen consecutive patients with mucoepidermoid carcinoma of the lung confirmed by pathology were reviewed retrospectively. All the patients had undergone unenhanced and contrast-enhanced examinations; one of them also had undergone 18F-FDG PET/CT examinations.
There were 6 males and 10 females with a mean age of 34.1 years. On CT plain scan, 14 out of 16 cases showed a well-defined endobronchus mass (n=12) or single peripheral nodule (n=2) with obstructive pneumonia or atelectasis (n=4), one case appeared a cavity in the tumor mass, and one presented diffuse circumferential wall thickening. Punctate calcification was observed in four cases (25%). Tumors showed mild (n=4, 25 %), moderate (n=6, 37.5%), and marked (n=6, 37.5%) degrees of contrast enhancement. Two patients had mediastinal lymph node metastasis, and one of them also had bone metastasis.
Mucoepidermoid carcinoma of the lung likely affects young adults. The common findings included a well-defined ovoid or rounded intraluminal mass; and uncommon findings included cavitation, diffuse thickening, or spiculation. Although CT manifestations of it are variable and nonspecific, a well-defined ovoid or lobulated intraluminal or lung peripheral mass with moderate to marked heterogeneous contrast enhancement may suggest the diagnosis of mucoepidermoid carcinoma of the lung. It should be included in the differential diagnosis of regional tumors.
本研究旨在分析肺黏液表皮样癌的 CT 各种表现,提高对该肿瘤的诊断效能。
回顾性分析 16 例经病理证实的肺黏液表皮样癌患者的资料,所有患者均行平扫及增强扫描,其中 1 例还进行了 18F-FDG PET/CT 检查。
男 6 例,女 10 例,平均年龄 34.1 岁。CT 平扫示 16 例中 14 例为边界清楚的支气管内肿块(n=12)或单发外周结节(n=2),伴阻塞性肺炎或肺不张(n=4),1 例肿瘤内见空洞,1 例呈肺内肿块弥漫性环形壁增厚。4 例(25%)见点状钙化。肿瘤呈轻度(n=4,25%)、中度(n=6,37.5%)和显著(n=6,37.5%)强化。2 例患者纵隔淋巴结转移,其中 1 例合并骨转移。
肺黏液表皮样癌好发于年轻成人,常见表现为边界清楚的卵圆形或类圆形腔内肿块,少见表现为空洞、弥漫性增厚或分叶状。虽然 CT 表现具有多样性和非特异性,但边界清楚的卵圆形或分叶状腔内或肺外周肿块伴中高度不均匀强化,可能提示肺黏液表皮样癌的诊断,应纳入肺内局灶性病变的鉴别诊断。