Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Int J Med Inform. 2012 May;81(5):291-5. doi: 10.1016/j.ijmedinf.2011.12.006. Epub 2012 Jan 5.
The study objective was to determine if computerized provider order entry (CPOE) systems impaired or enhanced workflow in the neonatal intensive care unit (NICU) by comparing the timing of administration of the first dose of antibiotics before and after CPOE system implementation.
We conducted a pre-post intervention comparative study of the length of time between admission and administration of initial antibiotics in neonates before and after a CPOE system was implemented. Clinical information and timing of antibiotic administration were collected on all inborn infants, who were admitted to the NICU in the first 4h of life and treated with antibiotics, for one year prior to the implementation of computerized order entry and for one year after the implementation.
Infants admitted to the NICU were similar in both periods (mean birth weight 2183 g vs. 2091 g, gestational age 33.3 weeks vs. 33.0 weeks). There was no significant difference in mean length of time from admission to antibiotic administration in the pre-CPOE group (131 min [CI 124-139]) compared to the post-CPOE group (125 min [CI 116-133]) (p=0.07). The mean time to pharmacy verification for a subset of patients was significantly shorter for patients in the post-CPOE group (61 ± 58 min) compared to the pre-CPOE group (88 ± 76 min) (p=<0.001).
While the introduction of a CPOE system in the NICU did not significantly improve antibiotic administration times, the timeliness of an important aspect of the medication process, time to pharmacy verification, was improved. These findings imply other factors are impeding workflow. Further studies are needed to evaluate how CPOE systems combined with patient care activities affect workflow and overall patient care.
本研究旨在通过比较电子医嘱录入系统(CPOE)实施前后新生儿重症监护病房(NICU)中抗生素首剂给药时间,确定 CPOE 系统是否会影响或改善 NICU 中的工作流程。
我们进行了一项前后干预比较研究,比较了 CPOE 系统实施前后 NICU 中新生儿入院至初始抗生素给药的时间。在 CPOE 实施前一年和实施后一年,我们收集了所有在出生后 4 小时内入住 NICU 并接受抗生素治疗的内在婴儿的临床信息和抗生素给药时间。
入住 NICU 的婴儿在两个时期的情况相似(平均出生体重 2183g 比 2091g,胎龄 33.3 周比 33.0 周)。CPOE 实施前组(131 分钟 [CI 124-139])与 CPOE 实施后组(125 分钟 [CI 116-133])从入院到抗生素给药的平均时间无显著差异(p=0.07)。对于亚组患者,药房核对的平均时间在 CPOE 实施后组(61±58 分钟)显著短于 CPOE 实施前组(88±76 分钟)(p<0.001)。
尽管 NICU 中引入 CPOE 系统并未显著改善抗生素给药时间,但药物处理的一个重要方面——药房核对的及时性得到了改善。这些发现表明,还有其他因素在阻碍工作流程。需要进一步研究评估 CPOE 系统与患者护理活动相结合如何影响工作流程和整体患者护理。