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[用光敏剂亚甲蓝对口腔、喉和咽恶性肿瘤进行光动力治疗的实验研究]

[Experimental studies for photodynamic therapy of malignant tumors of the mouth cavity, larynx and pharynx with the photosensitizer methylene blue].

作者信息

Kleemann D

机构信息

Hals-Nasen-Ohren-Klinik, Bereiches Medizin der Wilhelm-Pieck-Universität Rostock.

出版信息

Laryngorhinootologie. 1990 Aug;69(8):437-9. doi: 10.1055/s-2007-998224.

DOI:10.1055/s-2007-998224
PMID:2222693
Abstract

Squamous-cell carcinomas of the upper aerodigestive tract can be destroyed in vitro through photosensitization with Methylene blue and subsequent radiation with red laser light. It is impossible to obtain the same results with sensitization or light radiation alone. The paper discusses the conditions under which this procedure might develop into a truly selective photodynamic therapy method.

摘要

上消化道鳞状细胞癌可通过亚甲蓝光敏化及随后的红色激光照射在体外被破坏。单独使用敏化剂或光照射无法获得相同的结果。本文讨论了该程序可能发展成为一种真正选择性光动力治疗方法的条件。

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Laryngorhinootologie. 1990 Aug;69(8):437-9. doi: 10.1055/s-2007-998224.
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Photodynamic therapy on the normal rabbit larynx with phthalocyanine and 5-aminolaevulinic acid induced protoporphyrin IX photosensitisation.用酞菁和5-氨基乙酰丙酸诱导原卟啉IX光敏化对正常兔喉进行光动力治疗。
Br J Cancer. 1996 Jul;74(1):49-58. doi: 10.1038/bjc.1996.314.