Department of Neurology, Baylor College of Medicine, Houston, TX, USA.
Epilepsy Behav. 2012 Feb;23(2):159-61. doi: 10.1016/j.yebeh.2011.11.003. Epub 2012 Jan 9.
Seizure-related head injuries (SRHIs) are among the most commonly encountered injuries in people with epilepsy (PWE). Whether head injury has an effect on preexisting epilepsy is not known. The purpose of this study was to systematically assess for any possible effects of SRHIs on seizure frequency and seizure semiology over a 2-year period. We identified 204 patients who have been followed at the Baylor Comprehensive Epilepsy Center from 2008 to 2010. SRHI occurred in 18.1% of the cohort. Most injuries (91%) were classified as mild. Though seizure frequency varied following head injury, overall seizure frequency was not significantly impacted by presence or absence of SRHI over the 2-year study period. Changes in seizure semiology were not observed in those with SRHIs. Although mild SRHI is common among PWE, it does not appear to have an effect on seizure characteristics over a relatively short period.
与癫痫发作相关的头部损伤(SRHIs)是癫痫患者(PWE)最常见的损伤之一。头部损伤是否对既有癫痫产生影响尚不清楚。本研究的目的是系统评估 2 年内 SRHIs 对癫痫发作频率和发作表现的任何可能影响。我们从 2008 年至 2010 年在 Baylor 综合癫痫中心随访了 204 名患者。该队列中 18.1%的患者发生了 SRHI。大多数损伤(91%)为轻度。尽管头部损伤后癫痫发作频率有所变化,但在 2 年的研究期间,SRHI 的存在或缺失并未显著影响癫痫发作频率。在发生 SRHIs 的患者中未观察到发作表现的变化。尽管轻度 SRHI 在 PWE 中很常见,但在相对较短的时间内,它似乎对癫痫特征没有影响。