Department of Anesthesia, Second Affiliated Hospital of Jiaxing College, Jiaxing, China.
Eur J Anaesthesiol. 2012 May;29(5):223-8. doi: 10.1097/EJA.0b013e32834f23a3.
The right internal jugular vein (RIJV) is often used for central venous catheterisation in patients undergoing major surgery. The efficacy of this route correlates with the diameter of the vein which can be influenced by airway pressure.
To investigate four positive airway pressures (PAPs) in mechanically ventilated patients and to determine the most suitable of these for RIJV catheterisation.
Prospective, randomised, controlled study.
Two Chinese medical centres.
Two hundred and forty patients scheduled for gastrointestinal tract surgery under general anaesthesia (male-to-female ratio, 135 : 105; American Society of Anesthesiologists' physical status class, I-III; age range, 19-81 years); patients were excluded from the study if they had a history of haematological disease, external neck injury, RIJV catheterisation, severe cardiovascular disease, RIJV thrombosis, injection-site infection, pneumothorax and pulmonary bulla.
They were randomised into four groups of 60, each to undergo RIJV catheterisation at a PAP of 0 (1 cmH2O = 0.098 kPa, group A); 15 (group B); 20 (group C); and 25 cmH2O (group D).
Primary outcomes were central venous pressure (CVP) and RIJV cross-sectional area which were measured before and during PAP; the number of catheterisations completed in 30 s; the number of first pass punctures; heart rate and mean arterial pressure which were monitored continuously; and the incidence of complications which included local haematoma, pneumothorax and internal carotid artery (ICA) puncture.
Two patients were excluded following ICA puncture, leaving 238 for analysis. In groups C and D, the CVP and the cross-sectional area of RIJV were significantly larger; the number completing catheterisation within 30 s and the number of first pass punctures increased significantly and was comparable between these two groups. Compared with groups A and B, the incidences of hypotension and bradycardia were significantly increased in groups C and D. The incidence of local haematoma was significantly increased in group D compared with other groups. RIJV catheterisation was completed successfully in all but two patients in group A.
A PAP of 20 cmH2O seems most suitable for successful RIJV catheterisation in mechanically ventilated patients. It is associated with an increase in cross-sectional RIJV area and CVP, which facilitate cannulation, and results in fewer puncture-related complications. However, meticulous haemodynamic monitoring is needed to avoid hypotension and bradycardia.
在接受大手术的患者中,通常使用右颈内静脉(RIJV)进行中心静脉置管。该途径的有效性与静脉直径相关,而静脉直径可受气道压力影响。
研究机械通气患者的四种正压通气(PAP)并确定最适合 RIJV 置管的 PAP。
前瞻性、随机、对照研究。
两家中国医疗机构。
240 名拟在全身麻醉下接受胃肠道手术的患者(男:女,135:105;美国麻醉医师协会身体状况分级,I-III 级;年龄范围,19-81 岁);如果患者有血液病史、颈部外伤、RIJV 置管、严重心血管疾病、RIJV 血栓形成、注射部位感染、气胸和肺大疱,则将其排除在研究之外。
他们被随机分为四组,每组 60 人,分别在 PAP 为 0(1 cmH2O = 0.098 kPa,A 组)、15(B 组)、20(C 组)和 25 cmH2O(D 组)时进行 RIJV 置管。
主要观察指标为中心静脉压(CVP)和 RIJV 横截面积,分别在 PAP 前后进行测量;30 秒内完成置管的数量;首次穿刺次数;连续监测心率和平均动脉压;以及并发症的发生率,包括局部血肿、气胸和颈内动脉(ICA)穿刺。
在 ICA 穿刺后,有 2 名患者被排除在外,238 名患者进行了分析。在 C 组和 D 组中,CVP 和 RIJV 横截面积显著增大;在 30 秒内完成置管的数量和首次穿刺次数显著增加,且两组之间相当。与 A 组和 B 组相比,C 组和 D 组的低血压和心动过缓发生率显著增加。与其他组相比,D 组局部血肿的发生率显著增加。除 A 组的 2 名患者外,所有患者均成功完成 RIJV 置管。
在机械通气患者中,20 cmH2O 的 PAP 似乎最适合成功进行 RIJV 置管。它与 RIJV 横截面积和 CVP 的增加相关,这有助于置管,并导致更少的穿刺相关并发症。然而,需要进行仔细的血流动力学监测,以避免低血压和心动过缓。