Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea.
Clin Nucl Med. 2012 Feb;37(2):148-51. doi: 10.1097/RLU.0b013e3182335fdc.
To assure the surgical completeness of the bilateral axillo-breast approach (BABA) endoscopic thyroidectomy (ET), we compared ET and open thyroidectomy (OT) by means of the radioactive iodine (RAI) uptake of remnant thyroid.
From January 2003 to May 2007, 46 patients who had received RAI ablation after total thyroidectomy because of papillary thyroid microcarcinoma were enrolled. Of total, 25 patients underwent ET and the other 21 underwent OT. The RAI activity of remnant thyroid was measured by the neck-to-skull uptake ratio on the first postoperative RAI ablation scan. Stimulated thyroglobulin levels, the total number of RAI ablation sessions, and doses of RAI for completion of ablation were also compared.
There were no significant differences in regards of the RAI uptake ratio, the stimulated thyroglobulin level, the total number of RAI ablation sessions, and doses of RAI for completion of ablation, between ET and OT groups.
The completeness of the surgical removal by BABA ET was comparable with that of OT. The BABA ET might give a safe option for patients with low-risk thyroid cancer.
为了确保双侧腋窝入路内镜甲状腺切除术(BABA ET)的手术完整性,我们通过残留甲状腺的放射性碘(RAI)摄取率比较了 ET 和开放性甲状腺切除术(OT)。
自 2003 年 1 月至 2007 年 5 月,共有 46 例因甲状腺乳头状微小癌行全甲状腺切除术后接受 RAI 消融的患者被纳入研究。其中 25 例行 ET,21 例行 OT。通过术后首次 RAI 消融扫描时颈颅摄取比来测量残留甲状腺的 RAI 活性。还比较了刺激甲状腺球蛋白水平、RAI 消融总次数和完成消融所需的 RAI 剂量。
ET 组和 OT 组在 RAI 摄取率、刺激甲状腺球蛋白水平、RAI 消融总次数和完成消融所需的 RAI 剂量方面均无显著差异。
BABA ET 手术切除的完整性与 OT 相当。对于低危甲状腺癌患者,BABA ET 可能是一种安全的选择。