Sethiya Neeraj K, Patel M B, Mishra S H
Herbal Drug Technology Laboratory, Pharmacy Department, Faculty of Technology and Engineering, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, India.
Pharmacogn Rev. 2010 Jan;4(7):49-57. doi: 10.4103/0973-7847.65326.
Nature is an inexhaustible source of secondary metabolites-different types of alkaloids, terpenoids, phenolics, and other classes of organic compounds. In the process of isolation, purification and determination of the structures of lead, with their biological effectiveness, every type of experimental tool and strategy, known too and developed over the years by various practitioners. The present review is an attempt to compile information on various aspects of Canscora decussata, "Shankhpushpi" of Indian traditional system of medicine. The phytoconstituents, such as phenolic compounds, xanthones, and triterpenoids were isolated from different parts of the plant. The plant possesses immunomodulatory, analgesic, anticonvulsant, antitubercular, antiinflammatory, spermicidal, central nervous system-depressive, and cardiostimulant properties. Clinical trials of marketed formulation showed very encouraging results.
自然界是次生代谢产物取之不尽的来源——不同类型的生物碱、萜类化合物、酚类化合物以及其他各类有机化合物。在分离、纯化和确定先导化合物结构及其生物活性的过程中，多年来各种从业者已知并开发了各类实验工具和策略。本综述旨在汇编有关印度传统医学体系中的“Shankhpushpi”（叉分草）各方面的信息。从该植物的不同部位分离出了酚类化合物、氧杂蒽酮和三萜类等植物成分。该植物具有免疫调节、镇痛、抗惊厥、抗结核、抗炎、杀精、中枢神经系统抑制和心脏刺激特性。市售制剂的临床试验显示出非常令人鼓舞的结果。
