Dutt V, Thakur S, Dhar V J, Sharma A
Guru Gobind Singh College of Pharmacy, Yamuna Nagar, Haryana, Punjab, India.
Pharmacogn Rev. 2010 Jul;4(8):185-94. doi: 10.4103/0973-7847.70916.
The review includes 103 references on the genus Gelsemium, and comprises ethnopharmacology, morphology, phytoconstituents, pharmacological reports, clinical studies and toxicology of the prominent species of Gelsemium. Alkaloids and iridoids constitute major classes of phytoconstituents of the genus. Most popular species of the genus are the Asian G. elegans and the two North American related species, G. sempervirens and G. rankinii. Gelsemium species are categorized under medicinal as well as poisonous plants. Amongst various species, G. elegans and G. sempervirens possess medicinal value, and have been traditionally used as nervous system relaxant. These plants have been explored exhaustively for their anticancer activity. In the concluding part, the future scope of Gelsemium species has been emphasized with a view to establish their multifarious biological activities and mode of actions.
该综述涵盖了103篇关于钩吻属植物的参考文献，内容包括钩吻属主要物种的民族药理学、形态学、植物成分、药理学报告、临床研究和毒理学。生物碱和环烯醚萜是该属植物的主要植物成分类别。该属最常见的物种是亚洲的钩吻和两种北美相关物种，即常绿钩吻和小花钩吻。钩吻属植物既被归类为药用植物，也被归类为有毒植物。在各种物种中，钩吻和常绿钩吻具有药用价值，传统上被用作神经系统松弛剂。人们对这些植物的抗癌活性进行了详尽的研究。在结论部分，强调了钩吻属植物未来的研究范围，以期确定它们多样的生物活性和作用方式。
