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散射技术在两亲分子领域的应用。

Application of scattering techniques in the domain of amphiphiles.

作者信息

Corti M, Cantú L

机构信息

Dipartimento di Elettronica, Università di Pavia, Italy.

出版信息

Adv Colloid Interface Sci. 1990 Aug;32(2-3):151-66. doi: 10.1016/0001-8686(90)80016-s.

DOI:10.1016/0001-8686(90)80016-s
PMID:2222903
Abstract

Light and neutron scattering techniques are discussed in connection with experiments on micellar solutions of gangliosides--amphiphilic molecules of biological origin. Micellar properties, like molecular weight, hydrodynamic radius and shape, are obtained with precise scattering measurements in conditions of negligible intermicellar interactions. It has also been verified that the GM1 ganglioside micelle does not change molecular weight and shape on addition of salt. Scattering techniques are also shown to be useful in studying intermicellar interactions, like the Coulomb repulsion between GM1 micelles, in the regime fo the long-range interactions obtainable at very low ionic strength.

摘要

结合对神经节苷脂(生物来源的两亲分子)胶束溶液的实验,讨论了光散射和中子散射技术。在胶束间相互作用可忽略不计的条件下,通过精确的散射测量可获得胶束性质,如分子量、流体力学半径和形状。还证实了加入盐后GM1神经节苷脂胶束的分子量和形状不会改变。散射技术也被证明在研究胶束间相互作用方面很有用,比如在极低离子强度下可获得的长程相互作用范围内GM1胶束间的库仑排斥作用。

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引用本文的文献

1
Intensive extrusion and occlusion of water in ganglioside micelles with thermal reversibility.神经节苷脂胶束中水分的强烈挤压与包封及热可逆性
Biophys J. 1998 Jun;74(6):3010-4. doi: 10.1016/S0006-3495(98)78008-7.
2
Interaction of gangliosides with proteins depending on oligosaccharide chain and protein surface modification.神经节苷脂与蛋白质的相互作用取决于寡糖链和蛋白质表面修饰。
Biophys J. 1998 Mar;74(3):1380-7. doi: 10.1016/S0006-3495(98)77850-6.
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Thermotropic phase behavior and stability of monosialoganglioside micelles in aqueous solution.
单唾液酸神经节苷脂胶束在水溶液中的热致相行为及稳定性
Biophys J. 1996 Apr;70(4):1761-8. doi: 10.1016/S0006-3495(96)79739-4.