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动脉脉搏的周边失真的准集总模型。

A quasi-lumped model for the peripheral distortion of the arterial pulse.

机构信息

Department of Materials Science, University of Ioannina, GR 45110 Ioannina, Greece.

出版信息

Math Biosci Eng. 2012 Jan 1;9(1):175-98. doi: 10.3934/mbe.2012.9.175.

Abstract

As blood circulates through the arterial tree, the flow and pressure pulse distort. Principal factors to this distortion are reflections form arterial bifurcations and the viscous character of the flow of the blood. Both of them are expounded in the literature and included in our analysis. The nonlinearities of inertial effects are usually taken into account in numerical simulations, based on Navier-Stokes like equations. Nevertheless, there isn't any qualitative, analytical formula, which examines the role of blood's inertia on the distortion of the pulse. We derive such an analytical nonlinear formula. It emanates from a generalized Bernoulli's equation for an an-harmonic, linear, viscoelastic, Maxwell fluid flow in a linear, viscoelastic, Kelvin-Voigt, thin, cylindrical vessel. We report that close to the heart, convection effects related to the change in the magnitude of the velocity of blood dominate the alteration of the shape of the pressure pulse, while at remote sites of the vascular tree, convection of vorticity, related to the change in the direction of the velocity of blood with respect to a mean axial flow, prevails. A quantitative comparison between the an-harmonic theory and related pressure measurements is also performed.

摘要

当血液在动脉树中循环时,流动和压力脉冲会发生扭曲。这种扭曲的主要因素是动脉分叉处的反射和血液流动的粘性。它们在文献中都有阐述,并包含在我们的分析中。基于纳维-斯托克斯类方程的数值模拟通常考虑惯性效应的非线性。然而,没有任何定性的、分析性的公式来检查血液惯性对脉冲失真的作用。我们推导出了这样一个分析性的非线性公式。它源于非线性伯努利方程,适用于线性、粘弹性、开尔文-伏格特、薄、圆柱形容器中的非线性、谐波、线性、粘弹性、马克斯韦尔流体流动。我们报告说,在靠近心脏的地方,与血液速度大小变化相关的对流效应主导着压力脉冲形状的变化,而在血管树的远程部位,与血液速度相对于平均轴向流动的方向变化相关的涡度对流则占主导地位。我们还对非谐波理论和相关压力测量进行了定量比较。

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