Center of Neurology, Division of Neuropsychology, Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
Neuropsychologia. 2012 May;50(6):1136-41. doi: 10.1016/j.neuropsychologia.2011.12.018. Epub 2012 Jan 3.
While unilateral spatial neglect after left brain damage is undoubtedly less common than spatial neglect after a right hemisphere lesion, it is also assumed to be less severe. Here we directly test this latter hypothesis using a continuous measure of neglect severity: the so-called Center of Cancellation (CoC). Rorden and Karnath (2010) recently validated this index for right brain damaged neglect patients. A first aim of the present study was to evaluate this new measure for spatial neglect after left brain damage. In a group of 48 left-sided stroke patients with and without neglect, a score greater than -0.086 on the Bells Test and greater than -0.024 on the Letter Cancellation Task turned out to indicate neglect behavior for acute left brain damaged patients. A second aim was to directly compare the severity of spatial neglect after left versus right brain injury by using the new CoC measure. While neglect is less frequent following left than right hemisphere injury, we found that when this symptom occurs it is of similar severity in acute left brain injury as in patients after acute right brain injury.
虽然左脑损伤后的单侧空间忽略无疑比右脑损伤后的空间忽略少见，但人们也认为它的严重程度较轻。在这里，我们使用一种连续的忽略严重程度测量方法：所谓的中心消除（CoC），直接检验了后一种假设。罗登和卡纳思（2010）最近验证了该指数对右脑损伤忽视患者的有效性。本研究的第一个目的是评估该新方法对左脑损伤后的空间忽略的适用性。在 48 名有和无忽略的左侧中风患者中，Bells 测试得分大于-0.086 和字母消除任务得分大于-0.024 表明急性左脑损伤患者存在忽略行为。第二个目的是通过使用新的 CoC 测量方法直接比较左脑和右脑损伤后空间忽略的严重程度。虽然左半球损伤后忽略的发生率低于右半球损伤，但我们发现，当这种症状发生时，在急性左脑损伤中与急性右脑损伤患者中的严重程度相似。
