Int J Immunopathol Pharmacol. 2011 Oct-Dec;24(4):1075-7. doi: 10.1177/039463201102400425.
Anetoderma is a benign condition characterized by round or oval macular lesions with focal loss of dermal elastic tissue resulting in localized areas of flaccid or herniated saclike skin. Often, the anetoderma is associated with immuno-mediated pathogenetic mechanism. In this article, we describe the association between anetoderma and autoimmune diseases, by underlining the role and the action of macrophages as a possible etiopathogenesis.
萎缩性皮肤异色症是一种良性疾病,其特征为圆形或椭圆形斑片状皮损,真皮弹性组织局灶性丧失,导致局部皮肤松弛或疝出样囊状。通常,萎缩性皮肤异色症与免疫介导的发病机制有关。本文通过强调巨噬细胞的作用和功能,探讨了萎缩性皮肤异色症与自身免疫性疾病之间的关系,提出巨噬细胞可能是其发病机制之一。