Kon' I Ia, Shilina N M, Gmoshinskaia M V, Ivanushkina T A
Vopr Pitan. 2011;80(4):73-8.
Studied the possible relationship between the growth rate of children who are breastfed, and the level of protein, fat, insulin-like growth factor- 1 (IGF-1), ghrelin, leptin, adiponectin in breast milk. Examined 71 pair--a mother and a healthy child, who is breastfed. All infants were divided into 3 groups: low, normal and high weight gain. Daily breast milk intake, the level of fat, protein and hormones proteins regulators of energy homeostasis (adiponectin, grelin, IGF-1 and leptin) in breast milk were measured at 1, 2 and 3 months of lactation. It was found that daily breast milk consumption was higher in the group of infants with high weight gain and the content of protein and fat in it did not differ in three groups. Total daily consumption of protein and fat with breast milk was higher in groups of infants with high weight gain. There was significantly higher IGF-1 level and the tendency to higher grelin level in breast milk of mothers of infants with higher weight gain. The possible link of breast milk hormones with growth velocity of breast-fed infants is discussed.
研究了母乳喂养儿童的生长速率与母乳中蛋白质、脂肪、胰岛素样生长因子-1(IGF-1)、胃饥饿素、瘦素、脂联素水平之间的可能关系。对71对母婴(母亲和健康的母乳喂养儿童)进行了研究。所有婴儿被分为3组:低体重增加组、正常体重增加组和高体重增加组。在哺乳1个月、2个月和3个月时,测量了每日母乳摄入量、母乳中脂肪、蛋白质以及能量稳态调节激素蛋白(脂联素、胃饥饿素、IGF-1和瘦素)的水平。结果发现,高体重增加组婴儿的每日母乳摄入量较高,且三组母乳中蛋白质和脂肪含量无差异。高体重增加组婴儿通过母乳摄入的蛋白质和脂肪总量更高。高体重增加组婴儿母亲的母乳中IGF-1水平显著更高,胃饥饿素水平有升高趋势。讨论了母乳激素与母乳喂养婴儿生长速度之间的可能联系。