Potoczek Anna
Klinika Psychiatrii Doroslych Katedry Psychiatrii UJ CM.
Psychiatr Pol. 2011 Jul-Aug;45(4):469-80.
The author examined psychiatrically a group of 106 patients with difficult asthma and 100 patients with aspirin-induced asthma.
106 consecutive adults with confirmed, physician-diagnosed difficult asthma and 100 patients with aspirin-induced asthma underwent a psychiatric interview and assessment using M.I.N.I 5.0, Beck Depression Inventory (BDI) and Panic And Agoraphobia Scale (PAS). Psychiatric assessment was performed by an experienced liaison psychiatrist according to ICD-10 and DSM-IV diagnosis. In the difficult asthma group there were 78 women (74%) and 28 men (26%). The average age was 51.3 (SD = 14.5) for women and 47.5 (SD = 12.7) for men. In aspirin induced asthma group there were 66 women (66%) and 34 men (34%). The average age was 52.7 (SD = 12.3) for women and 48.8 (SD = 13.0) for men.
In difficult asthma both panic and depressive symptoms were statistically much more severe than in aspirin-induced asthma. Comorbidity between panic and depressive symptoms was almost equal in women and men with difficult asthma, but in aspirin-induced asthma, comorbidity was more common among women than men. Panic-depression comorbidity is regarded as a predictor of especially severe course and outcome of psychiatric disorder.
It is possible that especially severe panic and depressive symptoms both with panic-depression comorbidity in women and men with difficult asthma have an impact on aethiology of this near-fatal and treatment resistant subtype of asthma.
作者对一组106例难治性哮喘患者和100例阿司匹林诱发哮喘患者进行了精神科检查。
106例经医生确诊的难治性哮喘成年患者和100例阿司匹林诱发哮喘患者接受了精神科访谈，并使用M.I.N.I 5.0、贝克抑郁量表（BDI）和惊恐及场所恐惧症量表（PAS）进行评估。由一位经验丰富的联络精神科医生根据ICD - 10和DSM - IV诊断标准进行精神科评估。难治性哮喘组中有78名女性（74%）和28名男性（26%）。女性的平均年龄为51.3岁（标准差 = 14.5），男性为47.5岁（标准差 = 12.7）。阿司匹林诱发哮喘组中有66名女性（66%）和34名男性（34%）。女性的平均年龄为52.7岁（标准差 = 12.3），男性为48.8岁（标准差 = 13.0）。
在难治性哮喘中，惊恐和抑郁症状在统计学上比阿司匹林诱发哮喘严重得多。难治性哮喘的女性和男性中，惊恐和抑郁症状的共病情况几乎相同，但在阿司匹林诱发哮喘中，女性的共病情况比男性更常见。惊恐 - 抑郁共病被视为精神障碍特别严重病程和结局的一个预测指标。
难治性哮喘的女性和男性中特别严重的惊恐和抑郁症状以及惊恐 - 抑郁共病可能对这种近乎致命且治疗抵抗的哮喘亚型的病因学产生影响。
