Department of Psychology, University of Gothenburg, Sweden.
Acta Neurol Scand. 2012 May;125(5):293-302. doi: 10.1111/j.1600-0404.2011.01638.x. Epub 2012 Jan 11.
The extent and depth of traumatic brain injury (TBI) remains a major determining factor together with the type of structural insult and its location, whether mild, moderate or severe, as well as the distribution and magnitude of inflammation and loss of cerebrovascular integrity, and the eventual efficacy of intervention. The influence of exercise intervention in TBI is multiple, ranging from anti-apoptotic effects to the augmentation of neuroplasticity. Physical exercise diminishes cerebral inflammation by elevating factors and agents involved in immunomodulatory function, and buttresses glial cell, cerebrovascular, and blood-brain barrier intactness. It provides unique non-pharmacologic intervention that incorporate different physical activity regimes, whether dynamic or static, endurance or resistance. Physical training regimes ought necessarily to be adapted to the specific demands of diagnosis, type and degree of injury and prognosis for individuals who have suffered TBI.
创伤性脑损伤 (TBI) 的程度和深度仍然是一个主要的决定因素，与结构性损伤的类型及其位置有关，无论是轻度、中度还是重度，以及炎症和脑血管完整性的分布和程度的丧失，以及最终干预的效果。运动干预对 TBI 的影响是多方面的，从抗细胞凋亡作用到增强神经可塑性。体育锻炼通过提高参与免疫调节功能的因素和物质来减轻脑内炎症，并支持神经胶质细胞、脑血管和血脑屏障的完整性。它提供了独特的非药物干预，包括不同的体育活动方案，无论是动态的还是静态的，耐力的还是阻力的。体育训练方案必须根据个体遭受 TBI 的诊断、类型和程度以及预后的具体需求进行调整。
