[双膦酸盐治疗可能是双侧自发性非典型股骨骨折的一个原因]

[Treatment with bisphosphonates as a possible cause of bilateral spontaneous atypical femoral fracture].

作者信息

Rasmussen Mathias, Lange Jeppe

机构信息

Ortopædkirurgisk Afdeling, Regionshospitalet Silkeborg, Falkevej 1-3, 8600 Silkeborg, Denmark.

出版信息

Ugeskr Laeger. 2012 Jan 9;174(1-2):32-3.

PMID:22233718

Abstract

In recent years, case reports have suggested an association between long-term bisphosphonate treatment and spontaneous atypical femoral fractures. We present a case with a 67 year-old female who was treated with bisphosphonate for eight years and within one year sustained bilateral spontaneous atypical femoral fractures preceded by uncharacteristic hip/thigh pain. X-ray of proximal femur is indicated in patients with long-term bisphosphonate use and non-traumatic hip/thigh pain.

摘要

近年来，病例报告提示长期双膦酸盐治疗与自发性非典型股骨骨折之间存在关联。我们报告一例67岁女性病例，该患者接受双膦酸盐治疗八年，在一年内双侧发生自发性非典型股骨骨折，骨折前有非特异性髋部/大腿疼痛。对于长期使用双膦酸盐且有非创伤性髋部/大腿疼痛的患者，建议进行股骨近端X线检查。