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数字反卷积增强放射治疗患者定位验证的门控图像的清晰度和对比度。

Numerical deconvolution to enhance sharpness and contrast of portal images for radiotherapy patient positioning verification.

机构信息

Clinic for Radiation Therapy, Pius Hospital, Oldenburg, Germany.

出版信息

Strahlenther Onkol. 2012 Feb;188(2):185-90. doi: 10.1007/s00066-011-0030-y. Epub 2012 Jan 12.

DOI:10.1007/s00066-011-0030-y
PMID:22234540
Abstract

PURPOSE

The quality of megavoltage clinical portal images is impaired by physical and geometrical effects. This image blurring can be corrected by a fast numerical two-dimensional (2D) deconvolution algorithm implemented in the electronic portal image device. We present some clinical examples of deconvolved portal images and evaluate the clinical advantages achieved by the improved sharpness and contrast.

MATERIALS AND METHODS

The principle of numerical 2D image deconvolution and the enhancement of sharpness and contrast thereby achieved are shortly explained. The key concept is the convolution kernel K(x,y), the mathematical equivalent of the smearing or blurring of a picture, and the computer-based elimination of this influence.

RESULTS

Enhancements of sharpness and contrast were observed in all clinical portal images investigated. The images of fine bone structures were restored. The identification of organ boundaries and anatomical landmarks was improved, thereby permitting a more accurate comparison with the x-ray simulator radiographs. The visibility of prostate gold markers is also shown to be enhanced by deconvolution.

CONCLUSION

The blurring effects of clinical portal images were eliminated by a numerical deconvolution algorithm that leads to better image sharpness and contrast. The fast algorithm permits the image blurring correction to be performed in real time, so that patient positioning verification with increased accuracy can be achieved in clinical practice.

摘要

目的

兆伏级临床射野影像的质量因物理和几何效应而受损。这种图像模糊可以通过电子射野影像装置中实现的快速二维(2D)数值反卷积算法来纠正。我们呈现了一些经反卷积后的射野影像的临床实例,并评估了通过提高清晰度和对比度所获得的临床优势。

材料与方法

简要解释了数值二维图像反卷积的原理以及由此实现的清晰度和对比度的增强。关键概念是卷积核 K(x,y),它是图像模糊或失真的数学等价物,通过计算机消除这种影响。

结果

所有研究的临床射野影像的清晰度和对比度都得到了增强。精细骨结构的图像得到了恢复。器官边界和解剖标志的识别得到了改善,从而可以更准确地与射线模拟器射线照片进行比较。反卷积还显示出前列腺金标记的可见度得到了增强。

结论

通过数值反卷积算法消除了临床射野影像的模糊效应,从而提高了图像的清晰度和对比度。快速算法允许实时进行图像模糊校正,从而可以在临床实践中实现更精确的患者定位验证。

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本文引用的文献

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Prostate image-guided radiotherapy by megavolt cone-beam CT.兆伏锥形束 CT 引导的前列腺图像引导放疗。
Strahlenther Onkol. 2011 Aug;187(8):473-8. doi: 10.1007/s00066-011-2241-7. Epub 2011 Jul 22.
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kV cone-beam CT-based IGRT: a clinical review.基于千伏锥形束 CT 的 IGRT:临床评价。
Strahlenther Onkol. 2011 May;187(5):284-91. doi: 10.1007/s00066-011-2236-4. Epub 2011 Apr 26.
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Evaluation of kV cone-beam ct performance for prostate IGRT: a comparison of automatic grey-value alignment to implanted fiducial-marker alignment.
基于锥形束计算机断层扫描的前列腺外照射自适应治疗方案
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Residual translational and rotational errors after kV X-ray image-guided correction of prostate location using implanted fiducials.使用植入式基准标记进行 kV X 射线图像引导校正前列腺位置后的残余平移和旋转误差。
Strahlenther Onkol. 2010 Oct;186(10):544-50. doi: 10.1007/s00066-010-2030-8. Epub 2010 Sep 30.
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Toxicity after intensity-modulated, image-guided radiotherapy for prostate cancer.调强适形、图像引导放疗治疗前列腺癌的毒性反应。
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Iterative 2D deconvolution of portal imaging radiographs.迭代二维重建的门控成像射线照片。
Z Med Phys. 2011;21(1):52-64. doi: 10.1016/j.zemedi.2010.08.001.
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Image-guided stereotactic body radiation therapy for clinically localized prostate cancer: preliminary clinical results.图像引导的立体定向体部放射治疗局限性前列腺癌:初步临床结果。
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Use of three-dimensional ultrasound in the detection of breast tumor bed displacement during radiotherapy.三维超声在放射治疗中检测乳房肿瘤床位移的应用。
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Innovative image-guided CyberKnife stereotactic radiotherapy for bladder cancer.膀胱癌的创新影像引导 CyberKnife 立体定向放疗。
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