Santos Paulo R
Sobral School of Medicine, Federal University of Ceará, Avenida Comandante Maurocélio Rocha Pontes, 100 CEP 62,042-280, Sobral, Ceará, Brazil.
BMC Res Notes. 2012 Jan 11;5:24. doi: 10.1186/1756-0500-5-24.
To identify objective and subjective indicators of death in prevalent hemodialysis (HD) patients in a follow-up study of 12 months.
The study included end-stage renal disease patients undergoing HD and analyzed demographic and laboratory data from the dialysis unit's records. Baseline data concerning socioeconomic status, comorbidity, quality of life level, coping style and depression were also assessed. For variables that differed in the comparison between survivors and non-survivors, Cox proportional hazards for death were calculated.
The mortality rate was 13.0%. Non-survivors differed in age, comorbidity, inclusion on the transplant waiting list and physical functioning score. The hazard ratios of death were 8.958 (2.843-28.223; p < 0.001) for comorbidity, 3.992 (1.462-10.902; p = 0.007) for not being on the transplant waiting list, 1.038 (1.012-1.066; p = 0.005) for age, and 0.980 (0.964-0.996; p = 0.014) for physical functioning.
Comorbidity, not being on the transplant waiting list, age and physical functioning, which reflects physical status, must be seen as risk indicators of death among patients undergoing HD.
在一项为期12个月的随访研究中，确定维持性血液透析（HD）患者死亡的客观和主观指标。
该研究纳入了接受HD治疗的终末期肾病患者，并分析了透析单位记录中的人口统计学和实验室数据。还评估了有关社会经济状况、合并症、生活质量水平、应对方式和抑郁的基线数据。对于幸存者和非幸存者之间存在差异的变量，计算死亡的Cox比例风险。
死亡率为13.0%。非幸存者在年龄、合并症、是否列入移植等待名单以及身体功能评分方面存在差异。合并症的死亡风险比为8.958（2.843 - 28.223；p < 0.001），未列入移植等待名单的为3.992（1.462 - 10.902；p = 0.007），年龄的为1.038（1.012 - 1.066；p = 0.005），身体功能的为0.980（0.964 - 0.996；p = 0.014）。
合并症、未列入移植等待名单、年龄以及反映身体状况的身体功能，必须被视为HD患者死亡的风险指标。
