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安全的磁共振成像扫描在起搏器患者中的应用:当前技术与未来方向。

Safe magnetic resonance image scanning of the pacemaker patient: current technologies and future directions.

机构信息

Department of Cardiology, Academic Teaching Hospital of the University of Freiburg, Schwarzwald-Baar Klinikum, Vöhrenbacher Street 23, 78050 Villingen-Schwenningen, Germany.

出版信息

Europace. 2012 May;14(5):631-7. doi: 10.1093/europace/eur391. Epub 2012 Jan 10.

Abstract

Magnetic resonance imaging (MRI) is the imaging modality of choice in many clinical situations, and its use is likely to grow due to expanding indications and an ageing population. Many patients with implantable devices are denied MRI except in cases of urgent need, and when scans must be performed they are complicated by the need for burdensome and costly personnel and monitoring requirements that have the net effect of restricting access to scans. Several small studies, enrolling a total of 344 patients, suggest that some patients with conventional systems may undergo MR examinations without clinically overt adverse events. However, a number of potential interactions exist between implantable cardiac devices and the static and gradient magnetic fields and modulated radio frequency (RF) fields generated during MR scans; nearly all studies have reported pacing capture threshold changes, troponin elevations, ectopy, unpredictable reed switch behaviour, and other 'subclinical' issues with pacemakers and implantable cardioverter-defibrillators (ICDs) in patients who have undergone MRI. Attention has turned to devices that are specifically designed to be safe in the MRI environment. A clinical study of one such device documented its ability to be exposed to MRI in a 1.5 T scanner without adverse impact on patient outcomes or pacemaker system function. Such new technologies may enable scanning of pacemaker and ICD patients with reduced concerns regarding the short- and long-term effects of MRI. As importantly, these devices may increase the number of centres that are able to safely perform MRI and, thus, expand access to scans for patients with these devices.

摘要

磁共振成像(MRI)是许多临床情况下的首选成像方式,由于适应证的扩大和人口老龄化,其使用可能会增加。许多植入设备的患者除非有紧急需要,否则不能进行 MRI,而且在必须进行扫描时,由于需要繁琐且昂贵的人员和监测要求,这实际上限制了他们进行扫描的机会。几项小型研究共纳入 344 名患者,表明一些使用传统系统的患者可以进行 MRI 检查而不会出现明显的临床不良事件。然而,植入式心脏设备与磁共振扫描期间产生的静态和梯度磁场以及调制射频(RF)场之间存在许多潜在的相互作用;几乎所有研究都报告了起搏器和植入式心律转复除颤器(ICD)患者的起搏捕获阈值变化、肌钙蛋白升高、异位、不可预测的簧片开关行为以及其他“亚临床”问题。人们已经开始关注专门设计为在 MRI 环境中安全的设备。一项针对此类设备的临床研究记录了其在 1.5T 扫描仪中暴露于 MRI 而不会对患者结局或起搏器系统功能产生不良影响的能力。这些新技术可能使起搏器和 ICD 患者在接受 MRI 检查时减少对 MRI 的短期和长期影响的担忧。同样重要的是,这些设备可能会增加能够安全进行 MRI 的中心数量,从而扩大了这些设备患者接受扫描的机会。

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