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魁北克省加拿大出生和移民妇女的产前抑郁症状:对情境风险因素的不同暴露和脆弱性。

Antenatal depressive symptoms among Canadian-born and immigrant women in Quebec: differential exposure and vulnerability to contextual risk factors.

机构信息

Department of Social and Preventive Medicine, University of Montreal, 1430 boul. du Mont-Royal, Outremont, Montreal, QC, H2V 4P3, Canada.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2012 Oct;47(10):1639-48. doi: 10.1007/s00127-011-0469-2. Epub 2012 Jan 12.

Abstract

PURPOSE

To examine the distribution of contextual risk factors for antenatal depression according to immigrant status and the length of stay in Canada, to assess the association between these risk factors and antenatal depression (AD) for Canadian-born and immigrant women, and to compare the vulnerability of Canadian-born and immigrant women to risk factors in relation to antenatal depression.

METHODS

Women were recruited at routine ultrasound examinations (16-20 weeks), at antenatal blood sampling (8-12 weeks), or in antenatal care clinics. Cross-sectional analysis was performed on the baseline sample consisting of 5,162 pregnant women. CES-D scale was used to investigate depression. Levels of exposure to the selected risk factors according to immigrant status and length of stay were assessed using Chi-square-test or the t test. All measures of association were assessed using logistic regression. Multiplicative interaction terms were constructed between each of the risk factors and immigrant status to reveal differential vulnerability between Canadian-born and immigrant women.

RESULTS

Prevalence of AD (CES-D ≥16 points) was higher in immigrants (32% [29.6-34.4]) than in Canadian-born women (22.8% IC 95% [21.4-24.1]). Immigrant women were significantly more exposed than Canadian-born women to adverse contextual risk factors such as high marital strain, lack of social support, poverty, and crowding. At the same level of exposure to risk factors, Canadian-born women presented higher vulnerability to AD when lacking social support (OR = 4.14 IC 95% [2.69; 6.37]) while immigrant women presented higher vulnerability to AD when lacking money for basic needs (OR = 2.98 IC 95% [2.06; 4.32]).

CONCLUSIONS

Important risk factor exposure inequalities exist between Canadian-born and immigrant pregnant women. Interventions should target poverty and social isolation. The observed high frequency of AD highlights the need to evaluate the effectiveness of preventive interventions of antenatal depression.

摘要

目的

根据移民身份和在加拿大的居住时间,研究产前抑郁的背景风险因素分布,评估这些风险因素与加拿大出生和移民妇女产前抑郁(AD)之间的关系,并比较加拿大出生和移民妇女对与产前抑郁相关的风险因素的脆弱性。

方法

在常规超声检查(16-20 周)、产前血样采集(8-12 周)或产前保健诊所招募妇女。对包括 5162 名孕妇在内的基线样本进行横断面分析。使用 CES-D 量表调查抑郁情况。根据移民身份和居住时间评估所选风险因素的暴露水平,采用卡方检验或 t 检验。使用逻辑回归评估所有关联度量。在每个风险因素和移民身份之间构建乘法交互项,以揭示加拿大出生和移民妇女之间的差异脆弱性。

结果

AD(CES-D≥16 分)在移民中的患病率(32%[29.6-34.4])高于加拿大出生妇女(22.8%IC95%[21.4-24.1])。移民妇女比加拿大出生妇女更容易接触到不利的环境风险因素,如婚姻压力大、缺乏社会支持、贫困和拥挤。在相同的风险因素暴露水平下,缺乏社会支持时,加拿大出生妇女对 AD 的易感性更高(OR=4.14 IC95%[2.69;6.37]),而缺乏基本生活需求资金时,移民妇女对 AD 的易感性更高(OR=2.98 IC95%[2.06;4.32])。

结论

加拿大出生和移民孕妇之间存在重要的风险因素暴露不平等。干预措施应针对贫困和社会隔离。观察到 AD 的高发病率突出表明需要评估预防产前抑郁干预措施的有效性。

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