University of Michigan, Ann Arbor, 48109-5604, USA.
Am J Obstet Gynecol. 2010 Jan;202(1):5-14. doi: 10.1016/j.ajog.2009.09.007.
The purpose of this study was to evaluate risk factors for antepartum depressive symptoms that can be assessed in routine obstetric care. We evaluated articles in the English-language literature from 1980 through 2008. Studies were selected if they evaluated the association between antepartum depressive symptoms and > or =1 risk factors. For each risk factor, 2 blinded, independent reviewers evaluated the overall trend of evidence. In total, 57 studies met eligibility criteria. Maternal anxiety, life stress, history of depression, lack of social support, unintended pregnancy, Medicaid insurance, domestic violence, lower income, lower education, smoking, single status, and poor relationship quality were associated with a greater likelihood of antepartum depressive symptoms in bivariate analyses. Life stress, lack of social support, and domestic violence continued to demonstrate a significant association in multivariate analyses. Our results demonstrate several correlates that are consistently related to an increased risk of depressive symptoms during pregnancy.
本研究旨在评估可在常规产科护理中评估的产前抑郁症状的危险因素。我们评估了 1980 年至 2008 年英语文献中的文章。如果研究评估了产前抑郁症状与≥1 个危险因素之间的关系，则选择这些研究。对于每个危险因素，2 位盲法、独立的审查员评估证据的总体趋势。共有 57 项研究符合入选标准。在单变量分析中，母亲焦虑、生活压力、抑郁史、缺乏社会支持、非意愿妊娠、医疗补助保险、家庭暴力、低收入、低教育程度、吸烟、单身状况和较差的关系质量与产前抑郁症状发生的可能性更大相关。在多变量分析中，生活压力、缺乏社会支持和家庭暴力仍然与抑郁症状发生的风险显著相关。我们的研究结果表明，有几个相关因素与怀孕期间抑郁症状风险的增加密切相关。
