天然产物合成中的导向芳基功能化：弗雷德里克霉素 A、那他霉素 B 以及拓扑酮 B 和 D。
Directed aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D.
机构信息
Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada.
出版信息
Beilstein J Org Chem. 2011;7:1475-85. doi: 10.3762/bjoc.7.171. Epub 2011 Oct 28.
Abstract
THIS IS A REVIEW OF OUR EFFORTS TOWARD THE SYNTHESIS OF A GROUP OF NATURAL PRODUCTS THAT DISPLAY NOTEWORTHY BIOLOGICAL ACTIVITY
Fredericamycin A, nothapodytine B, and topopyrones B and D. In each case, directed aromatic functionalization methodology greatly facilitated the assembly of the key molecular subunits.
摘要
这是对我们合成一组具有显著生物活性天然产物的努力的综述
弗雷德里克霉素 A、那他泊汀 B 和拓扑吡喃酮 B 和 D。在每种情况下，定向芳构化方法极大地促进了关键分子亚基的组装。
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