Krivorot'ko P V, Semiglazov V V, Kanaev S V, Novikov S N, Pen'kov K D, Nikitina I V, Zhil'tsova E K
Vopr Onkol. 2011;57(5):627-35.
Recently, the rates of early stage breast cancers involving breast-conserving therapy have increased due to use of mammography screening. Morever, a patient's desire to keep the breast is now considered to be a factor which determines the surgery tactics. However, there has been so far no consensus on optimal extent of surgery capable of preventing local recurrence. In order to precisely estimate such risk it is essential to take into account factors such as tumor size, surgical margin status and age. Besides, correlations between certain subtypes of breast cancer and various associated risks of local recurrence are to be established. Another important factor is to devise the necessary subsequent radiotherapy.
近年来，由于乳腺钼靶筛查的应用，接受保乳治疗的早期乳腺癌比例有所上升。此外，患者保留乳房的意愿如今被视为决定手术策略的一个因素。然而，对于能够预防局部复发的最佳手术范围，目前尚无共识。为了精确评估此类风险，必须考虑肿瘤大小、手术切缘状态和年龄等因素。此外，还需确定乳腺癌某些亚型与局部复发各种相关风险之间的关联。另一个重要因素是设计必要的后续放疗。
