Hotchkiss Brain Institute, Department of Psychiatry, University of Calgary, Alberta, Canada.
Curr Pharm Des. 2012;18(4):558-65. doi: 10.2174/138161212799316082.
There is a strong impetus in the psychosis research field to develop interventions that aim to prevent the onset of psychotic disorders. Over the past 15 years there has been a tremendous development in the work aimed at understanding the pre-psychotic period. More recently there has been a focus on developing and testing treatments both pharmacological and psychological that could potentially prevent or delay the onset of psychosis. One of the psychological treatments that has received the most attention is cognitive behavioral therapy (CBT). Relatively few trials have been completed and this paper reviews the existing trials. Implications of these trials for the treatment of this early phase as well as for designing future studies are discussed.
在精神病学研究领域,有一种强烈的动力,旨在开发干预措施,以预防精神病的发生。在过去的 15 年中,人们在旨在了解精神病前期的工作方面取得了巨大进展。最近,人们的注意力集中在开发和测试潜在的预防或延缓精神病发作的药物和心理治疗上。受到最多关注的心理治疗之一是认知行为疗法(CBT)。完成的试验相对较少,本文回顾了现有的试验。讨论了这些试验对这一早期阶段治疗以及未来研究设计的意义。