Kulitskaia V I, Fedichkina T V, Sevast'ianova T V, Kuz'mina N S
Biull Eksp Biol Med. 1990 Jul;110(7):22-4.
In experiments on 10 dogs with external blood loss and reinfusion it was demonstrated, that in hemorrhagic and posthemorrhagic periods oxygen consumption by the organism is determined not only by O2 demands of the large circulation tissues, but to a great extent by demands in O2 in the system of lesser circulation, what is being evidenced by activation of the metabolic function of the lungs. It turned out that in pathogenesis of postinfusion respiratory insufficiency reactions of lipid oxidation in the lungs play a significant role.
在对10只进行体外失血和再输血的狗所做的实验中表明,在出血期和出血后期,机体的耗氧量不仅取决于大循环组织对氧气的需求,而且在很大程度上还取决于小循环系统对氧气的需求,肺部代谢功能的激活就证明了这一点。结果发现,在输液后呼吸功能不全的发病机制中,肺部脂质氧化反应起了重要作用。