Basu S, Kumar A
Banaras Hindu University, Varanasi, India.
J Wound Care. 2011 Dec;20(12):587-9. doi: 10.12968/jowc.2011.20.12.587.
Ecthyma gangrenosum is a well-recognised cutaneous infection in critically ill and immunocompromised patients. It is commonly associated with Pseudomonas aeruginosa septicaemia. Classic lesions of ecthyma gangrenosum comprise deep ulcers with ecchymotic, gangrenous centres, bright red areolae and typical raised, purplish, indurated, rolled-out edges. We report ecthyma gangrenosum in a premature low-birth-weight neonate, delivered at home to a third gravida mother with history of chorioamnionitis. He was admitted to a private hospital on third day of life, with a diagnosis of early-onset neonatal sepsis and received multiple antibiotics over next 22 days. The infant was referred to the paediatrics emergency department of Sir Sunderlal Hospital, Banaras Hindu University in a condition of shock, pneumonitis and generalised sepsis. Two gangrenous ulcers with gray-black eschar were present, one over the neck and another over the back. He was diagnosed as a case of neonatal sepsis with ecthyma gangrenosum. Blood culture revealed growth of Pseudomonas aeruginosa, sensitive only to imipenem. The infant died the day following admission.
坏疽性脓皮病是危重症和免疫功能低下患者中一种广为人知的皮肤感染。它通常与铜绿假单胞菌败血症相关。坏疽性脓皮病的典型皮损包括中央有瘀斑、呈坏疽性的深部溃疡,鲜红色的晕,以及典型的隆起、紫色、硬结、外翻的边缘。我们报告了一例早产低体重新生儿发生坏疽性脓皮病的病例,该新生儿在家中出生,其母亲为第三次怀孕,有绒毛膜羊膜炎病史。患儿出生第三天入住一家私立医院,诊断为早发型新生儿败血症,在接下来的22天里接受了多种抗生素治疗。该婴儿因休克、肺炎和全身性败血症被转诊至贝拿勒斯印度教大学苏德拉尔拉尔爵士医院儿科急诊科。患儿有两处坏疽性溃疡,伴有灰黑色焦痂,一处在颈部,另一处在背部。他被诊断为新生儿败血症合并坏疽性脓皮病。血培养显示有铜绿假单胞菌生长,仅对亚胺培南敏感。患儿入院次日死亡。