Pineda A A, Valbonesi M
Baillieres Clin Haematol. 1990 Apr;3(2):385-403. doi: 10.1016/s0950-3536(05)80056-3.
Interest in and use of IBS have increased recently. This form of haemotherapy involves the retrieval of blood shed perioperatively. IBS, together with other forms of ABT, has gained a prominent role in transfusion medicine, largely due to an increased awareness of the risks associated with transfusion of homologous blood. In addition to conserving erythrocytes, IBS prevents disease transmission, other adverse transfusion reactions, and alloimmunization to antigens in blood cells and plasma which may result from homologous blood use. An array of IBS devices is presently available, ranging from disposable canisters to complete processing systems. The devices are capable of recovering, filtering, washing and reinfusing shed erythrocytes. They can be divided into slow-flow and rapid-flow systems based on the rapidity of blood processing. Most systems use a dual channel aspiration cannula through which shed blood is aspirated and mixed with anticoagulant solution. The salvage procedure requires operator control at every step, even for the highly automated instruments. Various health care personnel have been trained to operate IBS equipment; a transfusion service nurse with blood bank expertise has proved to be a highly reliable operator in our practice. Extensive clinical observation has shown that salvaged erythrocytes function and survive normally. IBS has been applied in many surgical fields; it has two relative contraindications: its use in areas affected by infection or malignancy. Operative procedures characterized by large blood losses provide a cost-efficient application of IBS, including cardiac surgery, orthopaedic procedures, trauma, vascular surgery, and liver transplantation. New, highly efficient technology is emerging that is capable of recovering other blood components. Consequently, what presently amounts to erythrocyte recovery will be expanded shortly to include platelets and plasma, with its many constituents.
近期,术中自体血回输(IBS)的关注度和使用率有所上升。这种血液疗法涉及围手术期失血的回收。IBS与其他形式的血液回收技术(ABT)一起,在输血医学中发挥了重要作用,这主要是因为人们越来越意识到输注异体血所带来的风险。除了保存红细胞外,IBS还能预防疾病传播、其他不良输血反应以及因使用异体血而可能导致的对血细胞和血浆中抗原的同种免疫。目前有一系列IBS设备可供使用,从一次性罐到完整的处理系统。这些设备能够回收、过滤、洗涤和回输流失的红细胞。根据血液处理的速度,它们可分为慢流系统和快流系统。大多数系统使用双通道吸引套管,通过它将流失的血液吸出并与抗凝溶液混合。即使是高度自动化的仪器,挽救程序的每一步也都需要操作员进行控制。已经对各种医护人员进行了操作IBS设备的培训;在我们的实践中,具有血库专业知识的输血服务护士已被证明是非常可靠的操作员。广泛的临床观察表明,回收的红细胞功能正常且能存活。IBS已应用于许多外科领域;它有两个相对的禁忌症:在受感染或恶性肿瘤影响的区域使用。以大量失血为特征的手术操作提供了IBS的经济有效应用,包括心脏手术、骨科手术、创伤手术、血管手术和肝移植。正在出现能够回收其他血液成分的新型高效技术。因此,目前仅限于红细胞回收的技术不久将扩展到包括血小板和血浆及其众多成分。