Dermatology, Pathology, and Preventive Medicine and Community Health, New Jersey Medical School, Newark, New Jersey 07103, USA.
J Am Acad Dermatol. 2012 Feb;66(2):187-98; quiz 199-200. doi: 10.1016/j.jaad.2011.09.039.
The differential diagnosis of SC includes malignant, premalignant, metastatic, inflammatory, and eczematoid disorders, along with photodermatoses and a few rare but important disorders of the lower lip. Current treatment options include topical, ablative, and surgical therapies. Several clinical challenges are also addressed, including the issue of obtaining a high-yield diagnostic biopsy specimen while minimizing patient morbidity, field-directed treatment for SC, and strategies for combination therapy.
SC 的鉴别诊断包括恶性、癌前病变、转移性、炎症性和湿疹样疾病，以及光皮病和少数罕见但重要的下唇疾病。目前的治疗选择包括局部、消融和手术治疗。还解决了几个临床挑战，包括在尽量减少患者发病率的情况下获得高产量诊断活检标本、针对 SC 的靶向治疗以及联合治疗策略的问题。
