Department of Dermatology, Baylor College of Medicine, Houston, TX 77005, USA.
Int J Dermatol. 2010 Nov;49(11):1225-34. doi: 10.1111/j.1365-4632.2010.04580.x.
All other factors being equal, the presence of actinic cheilitis, a pre-invasive malignant lesion of the lips, doubles the risk of squamous cell carcinoma developing in this anatomic area. Various forms of local ablation,immunomodulation and surgical extirpation have been proposed as therapeutic interventions. This paper critically evaluates the available medical literature to highlight the evidence-based strength of each recommended therapy for actinic cheilitis. Vermilionectomy remains the gold standard for efficacy; trichloroacetic acid application is easy and convenient, but the least efficacious overall.
在其他因素相同的情况下，光化性唇炎的存在——唇部的一种癌前恶性病变——会使该解剖区域发生鳞状细胞癌的风险增加一倍。各种形式的局部消融、免疫调节和手术切除已被提议作为治疗干预措施。本文批判性地评估了现有的医学文献，以强调每种推荐疗法治疗光化性唇炎的循证强度。唇红切除术仍然是疗效的金标准；三氯乙酸应用简单方便，但总体效果最差。
