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我们能否通过控制食物暴露的时间来预防食物过敏?

Can we prevent food allergy by manipulating the timing of food exposure?

机构信息

Division of Allergy and Immunology and Center for Immunology and Microbial Diseases, Albany Medical College, 47 New Scotland Avenue MC # 151, Albany, NY 12208, USA.

出版信息

Immunol Allergy Clin North Am. 2012 Feb;32(1):51-65. doi: 10.1016/j.iac.2011.11.007. Epub 2011 Dec 16.

DOI:10.1016/j.iac.2011.11.007
PMID:22244232
Abstract

Prevention of food allergies by maternal and infant feeding practices serves as a simple, inexpensive approach to address the growing number of subjects with food allergies in comparison with any emerging interventional therapies for existing food allergies, such as oral immunotherapy. This article provides a careful evaluation of the rationale and existing data on the effect of timing of the introduction of food allergens (during pregnancy, lactation, and early childhood) on the development of specific food allergies.

摘要

通过母婴喂养方式预防食物过敏是一种简单、廉价的方法,可以解决越来越多的食物过敏患者的问题,而相比之下,针对现有的食物过敏,如口服免疫疗法,任何新兴的干预治疗方法都较为复杂。本文仔细评估了食物过敏原(孕期、哺乳期和幼儿期)引入时间对特定食物过敏发展的影响的原理和现有数据。

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引用本文的文献

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Executive summary: Evaluating the evidence base to support the inclusion of infants and children from birth to 24 mo of age in the Dietary Guidelines for Americans--"the B-24 Project".执行摘要:评估证据基础以支持将出生至 24 个月龄的婴儿和儿童纳入《美国人膳食指南》——“B-24 项目”。
Am J Clin Nutr. 2014 Mar;99(3):663S-91S. doi: 10.3945/ajcn.113.072140. Epub 2014 Feb 5.
2
Food allergy diagnosis and therapy: where are we now?食物过敏的诊断和治疗:我们现在在哪里?
Immunotherapy. 2013 Sep;5(9):931-44. doi: 10.2217/imt.13.93.