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食物过敏:流行病学与自然史

Food allergy: epidemiology and natural history.

作者信息

Savage Jessica, Johns Christina B

机构信息

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, 1 Jimmy Fund Way, Smith Building, Room 516c, Boston, MA 02115, USA; Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, 1 Jimmy Fund Way, Smith Building, Room 626, Boston, MA 02215, USA.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, 1 Jimmy Fund Way, Smith Building, Room 516c, Boston, MA 02115, USA.

出版信息

Immunol Allergy Clin North Am. 2015 Feb;35(1):45-59. doi: 10.1016/j.iac.2014.09.004. Epub 2014 Nov 21.

DOI:10.1016/j.iac.2014.09.004
PMID:25459576
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4254585/
Abstract

The prevalence of food allergy is rising for unclear reasons, with prevalence estimates in the developed world approaching 10%. Knowledge regarding the natural course of food allergies is important because it can aid the clinician in diagnosing food allergies and in determining when to consider evaluation for food allergy resolution. Many food allergies with onset in early childhood are outgrown later in childhood, although a minority of food allergy persists into adolescence and even adulthood. More research is needed to improve food allergy diagnosis, treatment, and prevention.

摘要

食物过敏的患病率出于不明原因正在上升,发达国家的患病率估计接近10%。了解食物过敏的自然病程很重要,因为它有助于临床医生诊断食物过敏,并确定何时考虑评估食物过敏是否缓解。许多在幼儿期发病的食物过敏在儿童后期会自愈,不过少数食物过敏会持续到青少年期甚至成年期。需要更多研究来改善食物过敏的诊断、治疗和预防。

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本文引用的文献

1
The natural history of egg allergy in an observational cohort.鸡蛋过敏的观察队列研究自然史。
J Allergy Clin Immunol. 2014 Feb;133(2):492-9. doi: 10.1016/j.jaci.2013.12.1041.
2
The natural history of IgE mediated wheat allergy in children with dominant gastrointestinal symptoms.儿童以胃肠道症状为主的 IgE 介导的小麦过敏的自然病程。
Allergy Asthma Clin Immunol. 2014 Feb 26;10(1):12. doi: 10.1186/1710-1492-10-12.
3
Prevalence of allergic sensitization in the United States: results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006.美国过敏致敏的流行情况:来自 2005-2006 年国家健康和营养调查(NHANES)的数据。
J Allergy Clin Immunol. 2014 Aug;134(2):350-9. doi: 10.1016/j.jaci.2013.12.1071. Epub 2014 Feb 9.
4
Increased food diversity in the first year of life is inversely associated with allergic diseases.生命的第一年增加食物多样性与过敏疾病呈负相关。
J Allergy Clin Immunol. 2014 Apr;133(4):1056-64. doi: 10.1016/j.jaci.2013.12.1044. Epub 2014 Feb 6.
5
Temporal trends and racial/ethnic disparity in self-reported pediatric food allergy in the United States.美国儿童自述食物过敏的时间趋势和种族/民族差异。
Ann Allergy Asthma Immunol. 2014 Mar;112(3):222-229.e3. doi: 10.1016/j.anai.2013.12.007. Epub 2014 Jan 7.
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Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment.食物过敏:流行病学、发病机制、诊断与治疗。
J Allergy Clin Immunol. 2014 Feb;133(2):291-307; quiz 308. doi: 10.1016/j.jaci.2013.11.020. Epub 2013 Dec 31.
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The natural history and clinical predictors of egg allergy in the first 2 years of life: a prospective, population-based cohort study.2 岁内儿童鸡蛋过敏的自然史和临床预测因素:一项前瞻性、基于人群的队列研究。
J Allergy Clin Immunol. 2014 Feb;133(2):485-91. doi: 10.1016/j.jaci.2013.11.032. Epub 2013 Dec 25.
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The impact of family history of allergy on risk of food allergy: a population-based study of infants.家族过敏史对食物过敏风险的影响:一项基于人群的婴儿研究。
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Evaluation of Ara h2 IgE thresholds in the diagnosis of peanut allergy in a clinical population.临床人群中Ara h2 IgE阈值在花生过敏诊断中的评估。
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