Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Am J Obstet Gynecol. 2012 Mar;206(3):211.e1-9. doi: 10.1016/j.ajog.2011.12.002. Epub 2011 Dec 11.
The purpose of this study was to estimate the total annual societal cost of uterine fibroid tumors in the United States, based on direct and indirect costs that include associated obstetric complications.
A systematic review of the literature was conducted to estimate the number of women who seek treatment for symptomatic fibroid tumors annually, the costs of medical and surgical treatment, the amount of work time lost, and obstetric complications that are attributable to fibroid tumors. Total annual costs were converted to 2010 US dollars. A sensitivity analysis was performed.
The estimated annual direct costs (surgery, hospital admissions, outpatient visits, and medications) were $4.1-9.4 billion. Estimated lost work-hour costs ranged from $1.55-17.2 billion annually. Obstetric outcomes that were attributed to fibroid tumors resulted in a cost of $238 million to $7.76 billion annually. Uterine fibroid tumors were estimated to cost the United States $5.9-34.4 billion annually.
Obstetric complications that are associated with fibroid tumors contributed significantly to their economic burden. Lost work-hour costs may account for the largest proportion of societal costs because of fibroid tumors.
本研究旨在根据直接和间接成本（包括相关产科并发症）估算美国子宫肌瘤的年度总社会成本。
对文献进行系统回顾，以估算每年因症状性子宫肌瘤寻求治疗的女性人数、医疗和手术治疗成本、因子宫肌瘤而损失的工作时间量以及与子宫肌瘤相关的产科并发症。将总年度成本转换为 2010 年的美元。进行了敏感性分析。
估计的年度直接成本（手术、住院、门诊和药物）为 41 亿至 94 亿美元。每年因子宫肌瘤而损失的工作小时成本范围为 15.5 亿至 172 亿美元。归因于子宫肌瘤的产科结局每年导致 2380 万美元至 77.6 亿美元的成本。估计子宫肌瘤每年使美国花费 59 亿至 344 亿美元。
与子宫肌瘤相关的产科并发症对其经济负担有重大影响。由于子宫肌瘤，工作时间损失成本可能占社会成本的最大比例。
