Kotwall C, Williams H T
Department of Surgery, University of Alberta Hospital, Edmonton.
Can J Surg. 1990 Oct;33(5):375-9.
A retrospective review of 185 patients who underwent truncal vagotomy and antrectomy for duodenal ulcer disease was carried out to determine the mortality and morbidity of the procedure. There were no deaths within 30 days of operation and only one patient died while in the hospital (0.54%). Twenty-one patients (11.4%) suffered early morbidity, 3 of them requiring a second operation. Follow-up was obtained in 83 patients and averaged 13.5 years. According to Visick's classification 75 patients (90.4%) were in class I or II; 5 patients (6%) were in class III and 3 patients (3.6%) in class IV. A recurrent ulcer developed in 2 of the 83 patients. In contrast, after highly selective vagotomy, the literature supports an unacceptable incidence of recurrent ulcer. Therefore, we must not prematurely cast aside vagotomy and antrectomy; it still remains a safe and acceptable procedure for duodenal ulcer disease.
对185例因十二指肠溃疡疾病接受迷走神经干切断术和胃窦切除术的患者进行了回顾性研究,以确定该手术的死亡率和发病率。术后30天内无死亡病例,仅1例患者在住院期间死亡(0.54%)。21例患者(11.4%)发生早期并发症,其中3例需要再次手术。对83例患者进行了随访,平均随访时间为13.5年。根据维西克分类,75例患者(90.4%)为I级或II级;5例患者(6%)为III级,3例患者(3.6%)为IV级。83例患者中有2例出现复发性溃疡。相比之下,高选择性迷走神经切断术后,文献报道的复发性溃疡发生率令人难以接受。因此,我们不能过早摒弃迷走神经干切断术和胃窦切除术;对于十二指肠溃疡疾病,它仍然是一种安全且可接受的手术方法。