Department of Radiation Oncology, University of Mississippi Medical Center, Jackson, MS, USA.
Med Oncol. 2012 Dec;29(4):2456-8. doi: 10.1007/s12032-011-0141-4. Epub 2012 Jan 15.
Cerebral radiation necrosis is a serious late complication after conventional radiotherapy that can present with focal neurologic deficits or with more generalized signs and symptoms of increased intracranial pressure, depending on the location. The incidence and severity of radionecrosis are dose-volume dependent. We report a case of cerebral radiation necrosis 5 years after radiotherapy for a maxillary sinus carcinoma.
放射性脑坏死是常规放疗后的一种严重迟发性并发症,其表现取决于病变部位,可出现局灶性神经功能缺损,也可出现更广泛的颅内压增高的体征和症状。放射性坏死的发生率和严重程度与剂量-体积有关。我们报告了 1 例上颌窦癌放疗 5 年后发生的放射性脑坏死。