Lipsky B A, Pecoraro R E, Ahroni J H
Medical Service, Veterans Affairs Medical Center, Seattle, Washington.
Clin Geriatr Med. 1990 Nov;6(4):747-69.
Foot lesions occur commonly among patients with diabetes, particularly the elderly and those with sensory neuropathy. Because of serious or recurrent infections and impaired healing processes, initially trivial lesions may progress to chronic nonhealing wounds, gangrene, or untreatable infections that can lead to limb amputation. Strategies to prevent amputation depend on understanding the multifactorial nature of diabetic foot disease; providing effective ongoing preventive care, including patient education; and prompt and aggressive treatment of foot lesions when they occur. The approach to treatment of infections depends on many factors, including the severity of the soft tissue infection, whether or not underlying bone or joints are involved, the types of infecting organisms, the patient's social situation, and his other medical problems. Proper diagnostic studies followed by appropriate antimicrobial therapy and local wound care can usually lead to resolution of these potentially serious infections.
足部病变在糖尿病患者中很常见,尤其是老年人和患有感觉神经病变的患者。由于严重或反复感染以及愈合过程受损,最初微不足道的病变可能会发展为慢性不愈合伤口、坏疽或无法治疗的感染,进而导致肢体截肢。预防截肢的策略取决于对糖尿病足病多因素性质的理解;提供有效的持续预防性护理,包括患者教育;以及在足部病变发生时及时、积极地进行治疗。感染的治疗方法取决于许多因素,包括软组织感染的严重程度、是否累及深层骨骼或关节、感染病原体的类型、患者的社会状况以及他的其他医疗问题。进行适当的诊断研究,随后给予适当的抗菌治疗和局部伤口护理,通常可以使这些潜在的严重感染得到解决。