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糖尿病足溃疡治疗中的生物力学概念

Biomechanical concepts in the treatment of ulcers in the diabetic foot.

作者信息

Gramuglia V J, Palmarozzo P M, Rzonca E C

机构信息

St. Barnabas Hospital, Bronx, New York.

出版信息

Clin Podiatr Med Surg. 1988 Jul;5(3):613-26.

PMID:3395952
Abstract

The diabetic patient and the associated pedal abnormalities pose a particularly challenging problem for the doctor from both a management and a prevention standpoint. The sequellae of diabetes mellitus have both neurologic and vascular origins. Neurologically, the diabetic is predisposed to peripheral and autonomic neuropathy, while vascular aberrations may manifest anywhere in the arterial network. Secondary breakdown of cutaneous and osseous structures are the direct result of a chronic insensitivity to pain and a faulty healing mechanism. Healing is, at best, delayed due to this inborn error of glucose metabolism. Ulceration in the diabetic patient remains one of the most troublesome complications of diabetes mellitus. The most diligent and expeditious treatment will fall short nonetheless, if the patient has not been completely educated concerning his affliction. The association of patient education and the response to therapy cannot be overstressed. The diabetic should be educated concerning proper foot care and should be made aware of the serious complications that may result from improper hygiene and pedal neglect. The patient should not assume a passive role in the treatment, but rather, actively participate in his recuperation and rehabilitation. Frankly, it is the patient's understanding of the disease process as it affects the foot and his willingness to accept part of the responsibility for his foot care that will determine the ultimate success of the treatment. The biomechanical considerations that follow the primary management of the acute presentation of diabetic lesions, are aimed at preventing further breakdown and lesion formation by minimizing the adverse effects of gait or ambulation. Biomechanical methods of treating or preventing neuropathic diabetic ulcers have been examined. The conventional medical management of neuropathic and angiopathic ulcers includes antibiosis, local debridement, and bed rest. Due to today's lifestyle, complete bed rest is not always convenient for the patient and even cooperative patients may neglect to use crutches or minimize the problem of their ulcer due to the absence of pain. The methods discussed afford the patient a more normal lifestyle; however, proper patient compliance is required. Patients who use the total contact cast must be willing to keep their weekly appointments zealously and report any problems pertaining to their treatment. After the ulcer has been closed, the patient and doctor must realize that the battle is only half over. Steps must be taken in order to deter one of the most frequent complications, reoccurrence of the ulcer.(ABSTRACT TRUNCATED AT 400 WORDS)

摘要

从管理和预防的角度来看,糖尿病患者及其相关的足部异常给医生带来了一个特别具有挑战性的问题。糖尿病的后遗症源于神经和血管两方面。在神经方面,糖尿病患者易患周围神经病变和自主神经病变,而血管异常可能出现在动脉网络的任何部位。皮肤和骨骼结构的继发性破坏是对疼痛长期不敏感和愈合机制不完善的直接结果。由于这种先天性的葡萄糖代谢错误,愈合充其量只能被延迟。糖尿病患者的溃疡仍然是糖尿病最麻烦的并发症之一。然而,如果患者没有完全了解自己的病情,最勤勉和迅速的治疗也会不足。患者教育与治疗反应之间的关联再怎么强调也不为过。应该对糖尿病患者进行正确足部护理的教育,并让他们意识到不当卫生和忽视足部可能导致的严重并发症。患者在治疗中不应扮演被动角色,而应积极参与康复和恢复过程。坦率地说,患者对影响足部的疾病过程的理解以及他愿意为足部护理承担部分责任,将决定治疗的最终成功。在糖尿病病变急性表现的主要管理之后进行的生物力学考量,旨在通过最小化步态或行走的不利影响来防止进一步的破坏和病变形成。已经研究了治疗或预防神经性糖尿病溃疡的生物力学方法。神经性和血管性溃疡的传统医学管理包括抗菌、局部清创和卧床休息。由于当今的生活方式,完全卧床休息对患者来说并不总是方便的,而且即使是配合的患者也可能由于没有疼痛而忽略使用拐杖或最小化溃疡问题。所讨论的方法为患者提供了更正常的生活方式;然而,需要患者的正确依从性。使用全接触石膏的患者必须愿意积极遵守每周的预约,并报告任何与治疗有关的问题。溃疡闭合后,患者和医生必须意识到战斗才刚刚过半。必须采取措施以防止最常见的并发症之一——溃疡复发。(摘要截选至400字)

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