药学服务对2型糖尿病患者生活质量的影响。
Impact of pharmaceutical care on quality of life in patients with type 2 diabetes mellitus.
作者信息
Sriram Shanmugam, Chack Lini Elizabeth, Ramasamy Rajeswari, Ghasemi Ali, Ravi Thengungal Kochupapy, Sabzghabaee Ali Mohammad
机构信息
Department of Pharmacy Practice, College of Pharmacy, Sri Ramakrishna Institute of Paramedical Sciences, India.
出版信息
J Res Med Sci. 2011 Mar;16 Suppl 1(Suppl1):S412-8.
BACKGROUND
Diabetes mellitus has become an international healthcare crisis that requires new approaches to prevent and treat it. The objective of this study was to evaluate the impact of pharmaceutical care on quality of life (QOL) in patients with type 2 diabetes mellitus.
METHODS
A prospective study on impact of pharmaceutical care on QOL in patients with type 2 diabetes mellitus was conducted in a private tertiary care teaching hospital in South India for a period of 8 months. Study was done on 120 eligible patients with type 2 diabetes mellitus enrolled randomly in the intervention group (with pharmaceutical care teachings) or the control (without drug related educations). The intervention group patients received pharmaceutical care through diabetes education, medication counseling, instructions on lifestyle that needed modifications (necessary for better drug function) and dietary regulations regarding their prescribed drugs, whereas the control group patients were deprived of any pharmaceutical care till the end of the study. The "Audit of Diabetes Dependent Quality of Life" standard questionnaire was used to assess the relevant parameters (including: Fasting Blood Glucose, HbA1c, Body Mass Index) and to evaluate the impact of the pharmaceutical care on the subjects. Data were analyzed using t-student test.
RESULTS
The intervention group showed an improvement in the quality of life score from -2.156 ± 0.12 at the baseline to -1.41 ± 0.13 at the final interview (p < 0.01). The average HbA1c values decreased from 8.44 ± 0.29% to 6.73 ± 0.21% (p < 0.01). There was a significant decrease in the fasting blood glucose from 195.57 ± 10.10 mg/dl to 107.25 ± 3.70 mg/dl between the baseline and the final interview in the intervention group (p < 0.01). The findings in the diabetes treatment satisfaction score also changed in a similar pattern.
CONCLUSIONS
The pharmaceutical care program was effective in improving the clinical outcome and the patients' QOL with type 2 diabetes mellitus.
背景
糖尿病已成为一场国际医疗危机，需要新的预防和治疗方法。本研究的目的是评估药学服务对2型糖尿病患者生活质量（QOL）的影响。
方法
在印度南部一家私立三级护理教学医院对药学服务对2型糖尿病患者生活质量的影响进行了一项为期8个月的前瞻性研究。对120名符合条件的2型糖尿病患者进行了研究，这些患者被随机纳入干预组（接受药学服务指导）或对照组（未接受药物相关教育）。干预组患者通过糖尿病教育、用药咨询、关于需要改变的生活方式（对更好的药物功能很必要）的指导以及关于其处方药的饮食规定接受药学服务，而对照组患者在研究结束前未接受任何药学服务。使用“糖尿病相关生活质量评估”标准问卷评估相关参数（包括：空腹血糖、糖化血红蛋白、体重指数），并评估药学服务对受试者的影响。数据采用t检验进行分析。
结果
干预组生活质量评分从基线时的-2.156±0.12提高到最终访谈时的-1.41±0.13（p<0.01）。平均糖化血红蛋白值从8.44±0.29%降至6.73±0.21%（p<0.01）。干预组基线和最终访谈之间空腹血糖从195.57±10.10mg/dl显著降至107.25±3.70mg/dl（p<0.01）。糖尿病治疗满意度评分的结果也呈类似变化模式。
结论
药学服务项目在改善2型糖尿病患者的临床结局和生活质量方面是有效的。
Zotero 插件