Neurology Pediatric Unit, Navarra Hospital Complex, Pamplona Department of Neuroradiology, Navarra Hospital Complex, Pamplona, Spain.
Eur J Neurol. 2012 Aug;19(8):1053-9. doi: 10.1111/j.1468-1331.2011.03640.x. Epub 2012 Jan 17.
The aim of this study is to analyze the proportional distribution of epilepsy and epileptic syndromes in children and to describe the magnetic resonance imaging (MRI) abnormalities found in these patients.
Data from 457 children aged 1 month to 15 years at the time of diagnosis of epilepsy were recorded. A routine MRI has been requested in all patients with epilepsy at diagnosis according to a standardized pediatric seizure protocol. Abnormalities on MRI were classified as either significant or non-significant (standardized scoring system). International League Against Epilepsy criteria were used for diagnoses.
The prevalence of significant MRI abnormalities was 21.9% (in infants 42.3%, in childhood 18.2%, and in adolescents 15.9%). The most common abnormalities included white-matter lesions (27.6%), volume loss (19.6%), gray-matter lesions (19.6%), and ventricular enlargement (12%).
The use of MRI and a reliable standardized scoring system at diagnosis of epilepsy in children identified a high rate of significant abnormalities findings. This may have important implications for practice guidelines in this population.
本研究旨在分析儿童癫痫和癫痫综合征的比例分布，并描述这些患者的磁共振成像（MRI）异常。
记录了 457 名年龄在 1 个月至 15 岁的诊断为癫痫的儿童的数据。根据标准化儿科癫痫方案，所有癫痫患者在诊断时均要求进行常规 MRI。将 MRI 异常分为有意义和无意义（标准化评分系统）。使用国际抗癫痫联盟标准进行诊断。
有意义 MRI 异常的患病率为 21.9%（婴儿为 42.3%，儿童为 18.2%，青少年为 15.9%）。最常见的异常包括白质病变（27.6%）、体积损失（19.6%）、灰质病变（19.6%）和脑室扩大（12%）。
在儿童癫痫的诊断中使用 MRI 和可靠的标准化评分系统，发现了很高比例的有意义的异常发现。这可能对该人群的实践指南有重要影响。
