National Neuroscience Institute, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia. E-mail:
Neurosciences (Riyadh). 2020 Oct;25(5):350-355. doi: 10.17712/nsj.2020.5.20200049.
To report the existence and describe the non-epileptic abnormalities, interictal epileptiform discharges, and seizures in routine electroencephalograms (EEGs) of infants in a tertiary hospital out-patient neurophysiology clinics.
This is a non-interventional, retrospective descriptive study that involved the review of 172 infants` EEGs conducted from July 2018 to June 2019 in King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia.
Total of 172 EEGs were reviewed; 152 routine EEGs for infants and 20 neonatal EEGs. Seventy-six (50%) EEGs were reported to be normal. Among the remaining EEGs, 54 were characterized by generalized slow background abnormalities (31.3 %), seven (4%) by background asymmetry, one (0.5%) by generalized low amplitude, and one (0.5 %) by an alternate trace that was dysmature for age. Interictal epileptiform discharges (IED) were present in 75 (43.6%) EEGs and they were focal in 72 (41.8%) EEGs, and generalized spike wave discharges were seen in only 3 (1.7%) EEGs with focal interictal epileptiform discharges. A diagnosis of hypsarrythmia was made from 15 (8.7%) EEGs. There were seizures in 11 (6.4%) EEGs, of which three were in neonates (15% of neonatal EEGs), and 8 in infants (4.6 % of infant EEGs).
Fifty % of routine infants` EEGs had abnormalities and hypsarrythmia was the most common abnormal background associated with seizures. Ictal discharges in form of generalized electrodecremental pattern associated clinically with epileptic spasm was the most common type of seizures.
报告在沙特阿拉伯利雅得的一家三级医院门诊神经生理诊所中，常规脑电图（EEG）中存在的非癫痫性异常、发作间期癫痫样放电和癫痫发作，并对其进行描述。
这是一项非介入性、回顾性描述性研究，共回顾了 2018 年 7 月至 2019 年 6 月期间在沙特阿拉伯利雅得法赫德国王医疗城进行的 172 例婴儿 EEG。
共回顾了 172 份 EEG，其中 152 份为婴儿常规 EEG，20 份为新生儿 EEG。76 份（50%）EEG 报告正常。在其余 EEG 中，54 份表现为广泛的背景缓慢异常（31.3%），7 份（4%）表现为背景不对称，1 份（0.5%）表现为广泛低幅度，1 份（0.5%）表现为与年龄不符的交替迹线不成熟。发作间期癫痫样放电（IED）见于 75 份（43.6%）EEG，其中 72 份（41.8%）为局灶性，仅 3 份（1.7%）为局灶性发作间期癫痫样放电的广泛棘波放电。15 份（8.7%）EEG 诊断为高度节律不齐。11 份（6.4%）EEG 中有癫痫发作，其中 3 例发生在新生儿（15%的新生儿 EEG），8 例发生在婴儿（4.6%的婴儿 EEG）。
50%的常规婴儿 EEG 存在异常，高度节律不齐是与癫痫发作相关的最常见异常背景。最常见的癫痫发作类型是表现为广泛电极减退模式的发作期放电，临床上与癫痫痉挛相关。
