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乳腺肌成纤维细胞瘤:一例诊断困难的病例报告

Myoid hamartoma of the breast that proved difficult to diagnose: a case report.

机构信息

Department of Endocrine and Breast Surgery, Kyoto Prefectural University of Medicine, Kawaramachi, Hirokoji, Kamikyo-ku, Kyoto, Japan.

出版信息

World J Surg Oncol. 2012 Jan 16;10:12. doi: 10.1186/1477-7819-10-12.

DOI:10.1186/1477-7819-10-12
PMID:22248347
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3271982/
Abstract

Myoid hamartomas of the breast are extremely rare breast lesions, with a poorly understood pathogenesis. We describe the case of a 38-year-old premenopausal woman who presenting with a mass in the left breast. Mammography revealed an oval mass that was partly indistinct, and ultrasonography showed a hypoechoic mass with a slightly irregular margin. Bilateral breast dynamic magnetic resonance imaging was performed for a more detailed evaluation. The images showed rapid initial enhancement and a microlobulated margin. Because the suspicion of malignancy was strong at that time, core needle biopsy was performed. Histologically, the tumor was identified as fibroadenoma. A case of myoid hamartoma of the breast that proved difficult to diagnose is reported, and discussed with reference to the literature.

摘要

乳腺肌样错构瘤极为罕见,其发病机制尚未完全阐明。我们报告了 1 例 38 岁绝经前女性,左乳出现肿块。乳腺 X 线摄影显示卵圆形部分边界不清的肿块,超声显示低回声肿块,边界略不规则。行双侧乳腺动态磁共振成像检查以进行更详细的评估。图像显示快速初始增强和微分叶状边缘。由于当时强烈怀疑恶性肿瘤,进行了空心针活检。组织学上,肿瘤被确定为纤维腺瘤。报告了 1 例乳腺肌样错构瘤病例,该病例诊断困难,并结合文献进行了讨论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/3271982/20276a3f35f8/1477-7819-10-12-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/3271982/1360001be8c0/1477-7819-10-12-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/3271982/9b4219714eef/1477-7819-10-12-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/3271982/73a6fed11c27/1477-7819-10-12-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/3271982/3398c7e9ce36/1477-7819-10-12-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/3271982/20276a3f35f8/1477-7819-10-12-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/3271982/1360001be8c0/1477-7819-10-12-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/3271982/9b4219714eef/1477-7819-10-12-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/3271982/73a6fed11c27/1477-7819-10-12-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/3271982/3398c7e9ce36/1477-7819-10-12-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20e9/3271982/20276a3f35f8/1477-7819-10-12-5.jpg

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引用本文的文献

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The diagnosis and treatment of 56 cases of breast hamartoma: a single-center analysis and a review of the literature.56例乳腺错构瘤的诊断与治疗:单中心分析及文献复习
Front Med (Lausanne). 2025 Jan 22;11:1494768. doi: 10.3389/fmed.2024.1494768. eCollection 2024.
3
Chromosomal Translocation t(5;12)(p13;q14) Leading to Fusion of High-mobility Group AT-hook 2 Gene With Intergenic Sequences From Chromosome Sub-Band 5p13.2 in Benign Myoid Neoplasms of the Breast: A Second Case.

本文引用的文献

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Myoid (Muscular) Hamartoma of the Breast: Case Report and Review of the Literature.乳腺肌样(肌肉)错构瘤:病例报告及文献复习
Breast Care (Basel). 2010;5(5):331-334. doi: 10.1159/000321341. Epub 2010 Oct 26.
2
A rare case of recurrent myoid hamartoma mimicking malignancy: imaging appearances.罕见病例:复发性肌样错构瘤酷似恶性肿瘤的影像学表现。
Korean J Radiol. 2010 Nov-Dec;11(6):683-6. doi: 10.3348/kjr.2010.11.6.683. Epub 2010 Oct 29.
3
Myoid hamartoma of breast with chondroid metaplasia: a case report.乳腺肌样错构瘤伴软骨化生:一例报告
染色体易位 t(5;12)(p13;q14)导致高迁移率族 AT 钩 2 基因与染色体 5p13.2 亚带间基因序列融合在良性乳腺肌源性肿瘤中的研究:第二例报告。
Cancer Genomics Proteomics. 2022 Jul-Aug;19(4):445-455. doi: 10.21873/cgp.20331.
4
Breast hamartoma: Unusual radiological presentation.乳腺错构瘤:不寻常的放射学表现。
Radiol Case Rep. 2020 Oct 23;15(12):2714-2717. doi: 10.1016/j.radcr.2020.10.015. eCollection 2020 Dec.
5
Mammary myoid hamartomas: reports of two cases and a review of the literature.乳腺肌样错构瘤:两例报告及文献复习
Int J Clin Exp Pathol. 2019 Jul 1;12(7):2398-2404. eCollection 2019.
6
Genetic Characterization of Myoid Hamartoma of the Breast.乳腺肌样错构瘤的遗传学特征。
Cancer Genomics Proteomics. 2019 Nov-Dec;16(6):563-568. doi: 10.21873/cgp.20158.
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Myoid hamartoma of the breast with focal chondromyoxid metaplasia and pseudoangiomatous stromal hyperplasia: A case report.乳腺肌样错构瘤伴局灶性软骨化生及假血管瘤样间质增生:病例报告
Oncol Lett. 2015 Apr;9(4):1787-1789. doi: 10.3892/ol.2015.2892. Epub 2015 Jan 23.
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Breast hamartoma: a clinicopathologic analysis of 27 cases and a literature review.乳腺错构瘤:27例临床病理分析及文献复习
Clinics (Sao Paulo). 2014 Aug;69(8):515-23. doi: 10.6061/clinics/2014(08)03.
9
Huge myoid hamartoma of the breast treated with reduction mammaplasty: report of a case.采用乳房缩小术治疗的巨大乳腺肌样错构瘤:病例报告
Surg Today. 2014 Dec;44(12):2369-73. doi: 10.1007/s00595-014-0833-4. Epub 2014 Jan 28.
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4
Myoid hamartoma of the breast: a case report and review of the literature.乳腺肌样错构瘤:一例病例报告及文献复习
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5
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