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[评估青春期对 1 型糖尿病(DM1)儿童和青少年进行不同强度体力活动后运动后血糖变化的影响]

[Assessment of the influence of puberty on changes in post exercise glycaemia after variable intensity physical effort in children and adolescents with diabetes mellitus type 1 (DM1)].

作者信息

Gazurek Dorota, Wójcik Małgorzta, Szmigiel Czesław, Dziatkowiak Hanna, Gąsiorowska Małgorzata

机构信息

Katedra Rehabilitacji Klinicznej Akademii Wychowania Fizycznego im. B. Czecha w Krakowie.

出版信息

Pediatr Endocrinol Diabetes Metab. 2011;17(4):188-94.

PMID:22248778
Abstract

INTRODUCTION

During the pubertal period the metabolic control is getting worse in the most of patients with type 1 diabetes mellitus (DM1). The insufficient metabolic control may impact the post-exercise glycaemia and cause the acute complications of the diabetes.

AIM OF THE STUDY

was to assess the influence of puberty on changes in post exercise glycaemia after variable intensity physical effort in children and adolescents with diabetes mellitus type 1 (DM1).

MATERIAL AND METHODS

The study group consisted of 88 children with DM1, 6 to 19 years of age, mean age 13.00±2.77 (SD). The subjects were divided into three groups according to pubertal stage (29 prepubertal subjects, 33 pubertal and 26 postpubertal adolescents with DM1). Three tests of increasing intensity were performed, each lasting 20 minutes on three consecutive days. The controls were the same children with no exercise.

RESULTS

In prepubertal subjects statistically significant lower levels of glycaemia were found 3 minutes (p<0.05) and 1 hour (p<0.05) after high intensity exercise in comparison to the controls. The pubertal subjects had statistically significant lower levels of glycaemy after high (p<0.001, p<0.01, p<0.05) and moderate intensity exercise (p<0.05, p<0.05, p<0.01 respectively) in all three check points compared to controls. The postpubertal subjects were found to have statistically significant lower levels of glycaemy after moderate intensity exercise 3 minutes (p<0.01) and 1 hour (p<0.05) compared to controls and after high intensity exercises 3 minutes after the exercise (p<0.05).

CONCLUSIONS

The rate of changes in post exercise glycaemy level depended on pubertal stage. The most significant decrease in post exercise glycaemy was observed in pubertal subjects.

摘要

引言

在青春期,大多数1型糖尿病(DM1)患者的代谢控制会变差。代谢控制不佳可能会影响运动后的血糖水平,并引发糖尿病急性并发症。

研究目的

评估青春期对1型糖尿病(DM1)儿童和青少年在不同强度体力活动后运动后血糖变化的影响。

材料与方法

研究组由88名6至19岁的DM1儿童组成,平均年龄13.00±2.77(标准差)。根据青春期阶段将受试者分为三组(29名青春期前受试者、33名青春期受试者和26名青春期后DM1青少年)。连续三天每天进行三次强度递增的测试,每次持续20分钟。对照组为相同的未进行运动的儿童。

结果

与对照组相比,青春期前受试者在高强度运动后3分钟(p<0.05)和1小时(p<0.05)血糖水平有统计学显著降低。与对照组相比,青春期受试者在所有三个检查点的高强度运动后(分别为p<0.001、p<0.01、p<0.05)和中等强度运动后(分别为p<0.05、p<0.05、p<0.01)血糖水平有统计学显著降低。与对照组相比,青春期后受试者在中等强度运动后3分钟(p<0.01)和1小时(p<0.05)以及高强度运动后3分钟(p<0.05)血糖水平有统计学显著降低。

结论

运动后血糖水平的变化率取决于青春期阶段。青春期受试者运动后血糖下降最为显著。

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1
[Assessment of the influence of puberty on changes in post exercise glycaemia after variable intensity physical effort in children and adolescents with diabetes mellitus type 1 (DM1)].[评估青春期对 1 型糖尿病(DM1)儿童和青少年进行不同强度体力活动后运动后血糖变化的影响]
Pediatr Endocrinol Diabetes Metab. 2011;17(4):188-94.
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