Rosenberg C, Hoffmann C O M, Mensel B, Puls R, Hosten N
Institut für Diagnostische Radiologie und Neuroradiologie, Universitätsmedizin Greifswald, Ferdinand-Sauerbruch-Str., 17475, Greifswald, Deutschland.
Radiologe. 2012 Jan;52(1):15-21. doi: 10.1007/s00117-011-2207-x.
Laser ablation (LA) is momentarily the only invasive ablation procedure besides radiofrequency ablation (RFA) which can be performed entirely under magnetic resonance imaging (MRI) guidance. The long-term outcome and morbidity profiles are broadly identical for both modalities, excluding the RFA-specific prevalence for skin burns. The technical and logistic disadvantages of LA have been overcome since the introduction of miniaturized two-component applicators. The main advantage of LA is its superior MRI compatibility. Interference-free imaging during LA allows MR thermometric real-time therapy control without the need for RF filters. High-resolution thermometry in the target zone only makes sense without the extinction artifact of a metal probe and this condition is met only by the glass fibers of LA. An independent therapy monitoring is crucial in modern scenarios of oncologic quality management.
激光消融（LA）目前是除射频消融（RFA）之外唯一一种可完全在磁共振成像（MRI）引导下进行的侵入性消融手术。除了RFA特有的皮肤烧伤发生率外，两种方式的长期疗效和发病率概况大致相同。自小型化双组件施源器问世以来，LA的技术和后勤方面的劣势已被克服。LA的主要优势在于其卓越的MRI兼容性。LA过程中无干扰成像使得无需射频滤波器即可进行磁共振温度实时治疗控制。只有在没有金属探头的消光伪影的情况下，目标区域的高分辨率温度测量才有意义，而LA的玻璃纤维仅满足这一条件。在现代肿瘤质量管理场景中，独立的治疗监测至关重要。
