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[化学物质对白化病大鼠后代生物学效应的评估]

[Evaluation of the biological effects of chemical substances on albino rat offspring].

作者信息

Rukavishnikov V S, Sosedova L M, Kapustina E A

出版信息

Gig Sanit. 2011 Nov-Dec(6):61-3.

PMID:22250396
Abstract

The paper provides the results of experimental studies of the impact of vinyl chloride or sublimate intoxication in male albino rats on the functional state of the nervous system of their offspring. Retarded sensorimotor development was revealed in the neonatal offspring. The pubertal offspring showed behavioral pattern disintegrity that was characterized by changes in motor activity and orientative-exploratory responses and by anxiety. There was abnormal impulse conduction in the neuromuscular apparatus of the hind legs of albino rats and morphological changes in the structure of nervous tissue.

摘要

该论文提供了雄性白化病大鼠氯乙烯或升汞中毒对其后代神经系统功能状态影响的实验研究结果。在新生后代中发现感觉运动发育迟缓。青春期后代表现出行为模式紊乱,其特征为运动活动、定向探索反应的变化以及焦虑。白化病大鼠后腿的神经肌肉装置存在异常冲动传导,神经组织结构也有形态学变化。

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