Gyasi H K, Zarroug A W, Matthew M, Joshi R, Daar A
Department of Anaesthesia, Royal Hospital, Seeb Muscat, Sultanate of Oman.
Can J Anaesth. 1990 Oct;37(7):778-85. doi: 10.1007/BF03006536.
Sickle cell disease (SCD) is associated with many pathological and functional abnormalities affecting all organ systems. Renal manifestations of SCD may result in end-stage renal disease (ESRD), which can be treated by chronic haemodialysis or renal transplantation. Renal transplantation was successfully performed in a 25-yr-old male with sickle cell beta-thalassaemia and nephrotic syndrome. We present a case report of this patient, a discussion of the renal complications associated with SCD and the perioperative management of a patient with SCD undergoing renal transplantation.
镰状细胞病（SCD）与影响所有器官系统的许多病理和功能异常相关。SCD的肾脏表现可能导致终末期肾病（ESRD），可通过慢性血液透析或肾移植进行治疗。一名患有镰状细胞β地中海贫血和肾病综合征的25岁男性成功接受了肾移植。我们在此报告该患者的病例，讨论与SCD相关的肾脏并发症以及接受肾移植的SCD患者的围手术期管理。
