调查气单胞菌属引起的菌血症，并与肝硬化患者的肠杆菌属引起的菌血症进行比较。
Investigation of Bacteremia due to Aeromonas Species and Comparison with That due to Enterobacteria in Patients with Liver Cirrhosis.
机构信息
Department of Physiology, School of Medicine, Tokai University, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.
出版信息
Gastroenterol Res Pract. 2011;2011:930826. doi: 10.1155/2011/930826. Epub 2011 Dec 29.
Background. The role of Aeromonas species (sp.) in bacteremia in Japanese patients with liver cirrhosis is poorly understood. Aim. To establish the importance of Aeromonas sp. as a cause of bacteremia in patients with liver cirrhosis. Methods. Clinical and serological features and short-term prognosis were retrospectively investigated and compared in Japanese patients with bacteremia due to Aeromonas sp. (n = 11) and due to enterobacteria (E. coli, Klebsiella sp., and Enterobacter sp.) (n = 84). Results. There were no significant differences in patients' clinical background, renal dysfunction, or short-term mortality rate between the two groups. However, in the Aeromonas group, the model for end-stage liver disease (MELD) score and Child-Pugh score were significantly higher than in the enterobacteria group. Conclusion. These results indicate that the severity of liver dysfunction in Aeromonas-induced bacteremia is greater than that in enterobacteria-induced bacteremia in Japanese patients with liver cirrhosis.
背景
在日本肝硬化患者中，气单胞菌属（sp.）在菌血症中的作用尚不清楚。目的：确定气单胞菌属作为肝硬化患者菌血症病因的重要性。方法：回顾性调查并比较了日本气单胞菌属（n=11）和肠杆菌（大肠杆菌、克雷伯菌属和肠杆菌属）（n=84）引起菌血症患者的临床和血清学特征及短期预后。结果：两组患者的临床背景、肾功能不全或短期死亡率无显著差异。然而，在气单胞菌组中，终末期肝病模型（MELD）评分和 Child-Pugh 评分明显高于肠杆菌组。结论：这些结果表明，在日本肝硬化患者中，气单胞菌引起的菌血症导致的肝功能不全严重程度大于肠杆菌引起的菌血症。
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