Mayer J E, Sanders S P, Jonas R A, Castañeda A R, Wernovsky G
Department of Cardiac Surgery, Children's Hospital, Boston, MA 02115.
Circulation. 1990 Nov;82(5 Suppl):IV139-45.
A successful outcome of an arterial switch operation (ASO) for dextro-transposition of the great arteries (D-TGA) depends in large part on the transfer of the coronary arteries to the neoaorta without distortion or narrowing. However, the origins and distribution of the coronary arteries are quite variable in D-TGA; therefore, the entire experience with ASO at the Children's Hospital in Boston was reviewed. From 1983 through November 1989, 314 patients underwent surgery for D-TGA with the intent to perform an ASO. An ASO was actually performed in 290 patients, and 20 patients died, with 12 deaths (4.2%) clearly related to problems with the coronary arteries (CA deaths). The ASO was aborted to a Senning operation in 24 patients (7.6%), primarily due to coronary anatomy. Eight coronary patterns were identified and related to the outcome of the ASO. In 182 patients with the "usual" coronary pattern for D-TGA (i.e., anterior descending and circumflex arteries from the left sinus and right coronary artery from the right sinus), five CA deaths occurred, and two patients had Senning operations. Sixty-seven patients had right coronary and circumflex arteries from the right sinus and anterior descending arteries from the left sinus. Three CA deaths occurred, and one patient had a Senning operation. Single right coronary artery was found in 14; 12 had ASOs with three CA deaths (25%); and two had Senning operations. One late death was due to diffuse narrowing of the single right coronary artery. Single left coronary artery occurred in 11 patients, and seven had ASO with no early but one late "sudden" death, whereas four had Senning operations.(ABSTRACT TRUNCATED AT 250 WORDS)
大动脉转位(D-TGA)动脉调转术(ASO)的成功结果在很大程度上取决于冠状动脉向新主动脉的转移,且无扭曲或狭窄。然而,D-TGA中冠状动脉的起源和分布差异很大;因此,回顾了波士顿儿童医院ASO的全部经验。从1983年至1989年11月,314例患者因D-TGA接受手术,旨在进行ASO。实际对290例患者进行了ASO,20例患者死亡,其中12例死亡(4.2%)与冠状动脉问题明确相关(冠状动脉死亡)。24例患者(7.6%)因冠状动脉解剖结构原因将ASO改为森宁手术。确定了八种冠状动脉模式,并与ASO的结果相关。在182例具有D-TGA“常见”冠状动脉模式的患者中(即左冠状动脉窦发出前降支和回旋支,右冠状动脉窦发出右冠状动脉),发生了5例冠状动脉死亡,2例患者接受了森宁手术。67例患者右冠状动脉窦发出右冠状动脉和回旋支,左冠状动脉窦发出前降支。发生了3例冠状动脉死亡,1例患者接受了森宁手术。发现14例患者为单支右冠状动脉;12例接受了ASO,3例冠状动脉死亡(25%);2例接受了森宁手术。1例晚期死亡是由于单支右冠状动脉弥漫性狭窄。11例患者为单支左冠状动脉,7例接受了ASO,无早期死亡,但有1例晚期“猝死”,4例接受了森宁手术。(摘要截断于250字)