Jeon Hyoseon, Kim Sang Kyong, Jeon BeomSeok, Park Kwang Suk
Interdisciplinary Program, Medical and Biological Engineering, Seoul National University, Graduate School, Republic of Korea.
Annu Int Conf IEEE Eng Med Biol Soc. 2011;2011:393-6. doi: 10.1109/IEMBS.2011.6090126.
The purpose of this paper is to assess Parkinson tremor estimating actual distance amplitude. We propose a practical, useful and simple method for evaluating Parkinson tremor with distance value. We measured resting tremor of 7 Parkinson Disease (PD) patients with triaxial accelerometer. Resting tremor of participants was diagnosed by Unified Parkinson's Disease Rating Scale (UPDRS) by neurologist. First, we segmented acceleration signal during 7 seconds from recorded data. To estimate a displacement of tremor, we performed double integration from the acceleration. Prior to double integration, moving average method was used to reduce an error of integral constant. After estimation of displacement, we calculated tremor distance during 1s from segmented signal using Euclidean distance. We evaluated the distance values compared with UPDRS. Averaged moving distance during 1 second corresponding to UPDRS 1 was 11.52 mm, that of UPDRS 2 was 33.58 mm and tremor distance of UPDRS 3 was 382.22 mm. Estimated moving distance during 1s was proportional to clinical rating scale--UPDRS.
本文的目的是通过估计实际距离幅度来评估帕金森震颤。我们提出了一种实用、有效且简单的方法，用于利用距离值评估帕金森震颤。我们使用三轴加速度计测量了7名帕金森病（PD）患者的静息震颤。参与者的静息震颤由神经科医生通过统一帕金森病评定量表（UPDRS）进行诊断。首先，我们从记录的数据中分割出7秒内的加速度信号。为了估计震颤的位移，我们对加速度进行了两次积分。在进行两次积分之前，使用移动平均法来减少积分常数的误差。在估计位移之后，我们使用欧几里得距离从分割后的信号中计算1秒内的震颤距离。我们将距离值与UPDRS进行了比较评估。与UPDRS 1相对应的1秒内平均移动距离为11.52毫米，UPDRS 2为33.58毫米，UPDRS 3的震颤距离为382.22毫米。1秒内估计的移动距离与临床评定量表——UPDRS成比例。
