Sprouse C, DeMenthon D, Gammie J, Burlina P
Johns Hopkins University Applied Physics Laboratory, Laurel, MD 20723, USA.
Annu Int Conf IEEE Eng Med Biol Soc. 2011;2011:4309-13. doi: 10.1109/IEMBS.2011.6091070.
We describe a method for performing modeling and simulation to predict the strain and stress experienced by tissues resulting from reconstructive cardiothoracic surgery. Stress computation is an important predictor of the quality and longevity of a repair and can therefore be used as guidance by a surgeon when deciding between various repair options. This paper uses the mitral valve repair as a use case because of its relevance and prevalence among reconstructive cardiac interventions. The modeling method presented here is informed by the patient specific anatomical structure recovered from real time 3D echocardiography. The method exploits hyperelastic models to infer realistic strain-stresses. We show through experiments using actual clinical data that results are in line with physiological expectations.
我们描述了一种进行建模和模拟的方法,以预测重建心胸外科手术对组织造成的应变和应力。应力计算是修复质量和持久性的重要预测指标,因此外科医生在决定各种修复方案时可将其用作指导。由于二尖瓣修复在重建心脏干预中的相关性和普遍性,本文将其作为一个应用案例。这里提出的建模方法是基于从实时三维超声心动图中获取的患者特定解剖结构。该方法利用超弹性模型来推断实际的应变-应力。我们通过使用实际临床数据进行的实验表明,结果符合生理预期。