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脉冲2.94微米铒钇铝石榴石激光皮肤磨削术——实验结果及首次临床应用

Pulsed 2.94-microns erbium-YAG laser skin ablation--experimental results and first clinical application.

作者信息

Kaufmann R, Hibst R

机构信息

Department of Dermatology, University of Ulm, FRG.

出版信息

Clin Exp Dermatol. 1990 Sep;15(5):389-93. doi: 10.1111/j.1365-2230.1990.tb02125.x.

Abstract

In the present study we compared skin-ablative effects produced by 2.94-microns pulsed erbium-YAG radiation on pig skin with those of the pulsed 308-nm UV excimer laser, continuous-wave CO2 laser, electrocautery and cold-knife surgery. Pulsed 2.94-microns radiation led to clean ablation craters and precise cuts with only minimal adjacent tissue damage followed by excellent healing without apparent scarring. These experimental results are consistent with those obtained from first clinical applications in the treatment of epidermal naevi and tattoos. However, since coagulation was insufficient to prevent bleeding and because of low repetition rates provided, the Er-YAG lasers currently available seem as yet of limited value for effective removal of deeper or larger lesions.

摘要

在本研究中,我们比较了2.94微米脉冲铒钇铝石榴石激光对猪皮肤产生的皮肤消融效果与脉冲308纳米准分子激光、连续波二氧化碳激光、电灼术和冷刀手术的效果。2.94微米脉冲辐射产生了干净的消融坑和精确的切口,仅对相邻组织造成最小程度的损伤,随后愈合良好,无明显疤痕。这些实验结果与首次临床应用于治疗表皮痣和纹身所获得的结果一致。然而,由于凝固不足以防止出血,且所提供的重复频率较低,目前可用的铒钇铝石榴石激光对于有效去除更深或更大的病变似乎价值有限。

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